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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNIH All Species: 34.24
Human Site: S96 Identified Species: 68.48
UniProt: O95406 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95406 NP_005767.1 144 16699 S96 Y M S R P V M S G P G L Y D P
Chimpanzee Pan troglodytes XP_001160456 163 19042 S115 Y M S R P V M S G P G L Y D P
Rhesus Macaque Macaca mulatta XP_001085263 136 15787 Y89 L A Y H I W R Y M S R P V M S
Dog Lupus familis XP_864395 160 18544 S112 Y M S R P V M S G P G L Y D P
Cat Felis silvestris
Mouse Mus musculus O35372 144 16694 S96 Y M S R P V M S A P G L Y D P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512553 152 18146 F99 G L N V P L L F Y H F W R Y F
Chicken Gallus gallus NP_001028178 144 16696 S96 Y M S R P V M S G P G L Y D P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001028278 144 16687 S96 Y M S H P I M S G P G L Y D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P49858 144 16912 S96 Y K N R P V M S G P G L Y D P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22361 145 16811 S96 Y A K R P V M S G P G I Y D P
Sea Urchin Strong. purpuratus XP_787571 144 16654 S96 Y A N R P V M S G P G L Y D A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53173 138 15911 L91 K I Y N K V Q L L D A T E I F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.3 94.4 90 N.A. 99.3 N.A. N.A. 67.1 99.3 N.A. 96.5 N.A. 68 N.A. 58.6 75.6
Protein Similarity: 100 88.3 94.4 90 N.A. 99.3 N.A. N.A. 75.6 100 N.A. 98.6 N.A. 84 N.A. 75.1 87.5
P-Site Identity: 100 100 0 100 N.A. 93.3 N.A. N.A. 6.6 100 N.A. 86.6 N.A. 86.6 N.A. 80 80
P-Site Similarity: 100 100 0 100 N.A. 93.3 N.A. N.A. 33.3 100 N.A. 93.3 N.A. 93.3 N.A. 86.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 54.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 0 0 0 0 0 0 9 0 9 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 9 0 0 0 75 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 17 % F
% Gly: 9 0 0 0 0 0 0 0 67 0 75 0 0 0 0 % G
% His: 0 0 0 17 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 9 0 0 9 9 0 0 0 0 0 9 0 9 0 % I
% Lys: 9 9 9 0 9 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 9 0 0 0 9 9 9 9 0 0 67 0 0 0 % L
% Met: 0 50 0 0 0 0 75 0 9 0 0 0 0 9 0 % M
% Asn: 0 0 25 9 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 84 0 0 0 0 75 0 9 0 0 67 % P
% Gln: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 67 0 0 9 0 0 0 9 0 9 0 0 % R
% Ser: 0 0 50 0 0 0 0 75 0 9 0 0 0 0 9 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % T
% Val: 0 0 0 9 0 75 0 0 0 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 0 9 0 0 0 % W
% Tyr: 75 0 17 0 0 0 0 9 9 0 0 0 75 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _