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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNIH All Species: 30.61
Human Site: T47 Identified Species: 61.21
UniProt: O95406 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95406 NP_005767.1 144 16699 T47 N P I D Q C N T L N P L V L P
Chimpanzee Pan troglodytes XP_001160456 163 19042 T47 N P I D Q C N T L N P V I V D
Rhesus Macaque Macaca mulatta XP_001085263 136 15787 D43 T D Y K N P I D Q C N T L N P
Dog Lupus familis XP_864395 160 18544 T47 N P I D Q C N T L N P T V E K
Cat Felis silvestris
Mouse Mus musculus O35372 144 16694 T47 N P I D Q C N T L N P L V L P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512553 152 18146 P47 S P I D Q C N P V H A R E R L
Chicken Gallus gallus NP_001028178 144 16696 T47 N P I D Q C N T L N P L V L P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001028278 144 16687 T47 N P I D Q C N T L N P L V L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P49858 144 16912 S47 N P I D Q C N S L N P L V L P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22361 145 16811 N47 N P I E Q C R N L N Q L I L P
Sea Urchin Strong. purpuratus XP_787571 144 16654 S47 N P I D Q C N S L N P L V L P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53173 138 15911 K43 N P I E L C S K V N K L I T P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.3 94.4 90 N.A. 99.3 N.A. N.A. 67.1 99.3 N.A. 96.5 N.A. 68 N.A. 58.6 75.6
Protein Similarity: 100 88.3 94.4 90 N.A. 99.3 N.A. N.A. 75.6 100 N.A. 98.6 N.A. 84 N.A. 75.1 87.5
P-Site Identity: 100 73.3 6.6 80 N.A. 100 N.A. N.A. 40 100 N.A. 100 N.A. 93.3 N.A. 66.6 93.3
P-Site Similarity: 100 93.3 13.3 80 N.A. 100 N.A. N.A. 60 100 N.A. 100 N.A. 100 N.A. 80 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 54.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 92 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 9 0 75 0 0 0 9 0 0 0 0 0 0 9 % D
% Glu: 0 0 0 17 0 0 0 0 0 0 0 0 9 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 92 0 0 0 9 0 0 0 0 0 25 0 0 % I
% Lys: 0 0 0 9 0 0 0 9 0 0 9 0 0 0 9 % K
% Leu: 0 0 0 0 9 0 0 0 75 0 0 67 9 59 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 84 0 0 0 9 0 75 9 0 84 9 0 0 9 0 % N
% Pro: 0 92 0 0 0 9 0 9 0 0 67 0 0 0 75 % P
% Gln: 0 0 0 0 84 0 0 0 9 0 9 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 0 0 9 0 9 0 % R
% Ser: 9 0 0 0 0 0 9 17 0 0 0 0 0 0 0 % S
% Thr: 9 0 0 0 0 0 0 50 0 0 0 17 0 9 0 % T
% Val: 0 0 0 0 0 0 0 0 17 0 0 9 59 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _