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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZIC2
All Species:
14.85
Human Site:
S378
Identified Species:
36.3
UniProt:
O95409
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95409
NP_009060.2
532
55006
S378
D
R
R
F
A
N
S
S
D
R
K
K
H
M
H
Chimpanzee
Pan troglodytes
XP_516806
404
43927
T254
V
N
H
I
R
V
H
T
G
E
K
P
F
P
C
Rhesus Macaque
Macaca mulatta
XP_001093759
1092
112511
S940
D
R
R
F
A
N
S
S
D
R
K
K
H
M
H
Dog
Lupus familis
XP_542652
472
50656
N321
K
A
K
Y
K
L
V
N
H
I
R
V
H
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q62520
530
54935
S378
D
R
R
F
A
N
S
S
D
R
K
K
H
M
H
Rat
Rattus norvegicus
NP_001101862
541
56791
S377
D
R
R
F
A
N
S
S
D
R
K
K
H
M
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989585
444
48146
T294
V
N
H
I
R
V
H
T
G
E
K
P
F
P
C
Frog
Xenopus laevis
Q9YIB7
497
53471
N339
K
A
K
Y
K
L
V
N
H
I
R
V
H
T
G
Zebra Danio
Brachydanio rerio
NP_571633
445
49055
H295
L
V
N
H
I
R
V
H
T
G
E
K
P
F
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P39768
609
66219
R338
R
F
A
N
S
S
D
R
K
K
H
S
H
V
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.1
48.5
81.7
N.A.
98.1
90.3
N.A.
N.A.
64
73.5
74.8
N.A.
35.6
N.A.
N.A.
N.A.
Protein Similarity:
100
65.7
48.5
82.3
N.A.
98.5
91.3
N.A.
N.A.
70.8
78.1
79.3
N.A.
47.4
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
6.6
N.A.
100
100
N.A.
N.A.
6.6
6.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
33.3
N.A.
100
100
N.A.
N.A.
13.3
33.3
13.3
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
10
0
40
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% C
% Asp:
40
0
0
0
0
0
10
0
40
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
20
10
0
0
0
0
% E
% Phe:
0
10
0
40
0
0
0
0
0
0
0
0
20
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
20
10
0
0
0
0
20
% G
% His:
0
0
20
10
0
0
20
10
20
0
10
0
70
0
50
% H
% Ile:
0
0
0
20
10
0
0
0
0
20
0
0
0
0
0
% I
% Lys:
20
0
20
0
20
0
0
0
10
10
60
50
0
0
0
% K
% Leu:
10
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
40
0
% M
% Asn:
0
20
10
10
0
40
0
20
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
20
10
20
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
40
40
0
20
10
0
10
0
40
20
0
0
0
0
% R
% Ser:
0
0
0
0
10
10
40
40
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
20
10
0
0
0
0
20
0
% T
% Val:
20
10
0
0
0
20
30
0
0
0
0
20
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _