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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGN
All Species:
35.76
Human Site:
S224
Identified Species:
71.52
UniProt:
O95427
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95427
NP_036459.1
931
105810
S224
G
H
A
H
R
P
S
S
R
D
Y
K
H
N
I
Chimpanzee
Pan troglodytes
XP_512161
931
105786
S224
G
H
A
H
R
P
S
S
R
D
Y
K
D
N
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533387
987
112230
S280
G
H
A
H
R
P
T
S
R
E
Y
K
D
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1S3
931
105027
S224
G
H
A
H
R
P
S
S
R
E
Y
K
D
N
I
Rat
Rattus norvegicus
NP_001094054
931
104957
S224
G
H
A
H
R
P
S
S
R
E
Y
K
D
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505836
960
108183
S252
G
H
A
H
R
P
A
S
R
E
Y
K
E
N
I
Chicken
Gallus gallus
XP_418994
933
104963
S226
G
H
A
H
R
P
Y
S
K
E
Y
K
E
N
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001121709
662
74613
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192083
529
59421
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_186787
993
112037
S264
G
H
A
H
R
P
Y
S
S
I
Y
L
N
N
V
Baker's Yeast
Sacchar. cerevisiae
P36051
919
105675
S234
G
H
S
Y
R
P
Y
S
A
E
Y
Y
D
N
V
Red Bread Mold
Neurospora crassa
Q7SAP1
996
110539
S242
G
H
S
Y
R
P
Y
S
K
E
Y
L
N
N
I
Conservation
Percent
Protein Identity:
100
99.3
N.A.
80.9
N.A.
87.3
87.2
N.A.
72.8
71.4
N.A.
44.4
N.A.
N.A.
N.A.
N.A.
35.3
Protein Similarity:
100
99.4
N.A.
86.3
N.A.
92.3
93.2
N.A.
84
83.8
N.A.
58.1
N.A.
N.A.
N.A.
N.A.
44.4
P-Site Identity:
100
93.3
N.A.
80
N.A.
86.6
86.6
N.A.
80
73.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
N.A.
93.3
N.A.
93.3
93.3
N.A.
93.3
86.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.6
38.5
40.3
Protein Similarity:
N.A.
N.A.
N.A.
56.7
59.5
57.2
P-Site Identity:
N.A.
N.A.
N.A.
60
46.6
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
73.3
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
67
0
0
0
9
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
17
0
0
42
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
59
0
0
17
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
84
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
84
0
67
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
67
% I
% Lys:
0
0
0
0
0
0
0
0
17
0
0
59
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
17
84
0
% N
% Pro:
0
0
0
0
0
84
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
84
0
0
0
50
0
0
0
0
0
0
% R
% Ser:
0
0
17
0
0
0
34
84
9
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
17
0
0
34
0
0
0
84
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _