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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGN
All Species:
20
Human Site:
S419
Identified Species:
40
UniProt:
O95427
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95427
NP_036459.1
931
105810
S419
R
K
F
D
E
V
V
S
L
C
K
E
L
I
H
Chimpanzee
Pan troglodytes
XP_512161
931
105786
S419
R
K
F
D
E
V
V
S
L
C
K
E
L
I
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533387
987
112230
S475
R
K
Y
D
E
A
V
S
L
C
K
E
L
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1S3
931
105027
S419
E
K
F
D
E
V
V
S
L
C
E
E
L
I
D
Rat
Rattus norvegicus
NP_001094054
931
104957
S419
E
K
F
D
D
V
V
S
L
C
E
E
L
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505836
960
108183
I447
L
Q
F
S
N
V
E
I
I
V
V
L
E
K
T
Chicken
Gallus gallus
XP_418994
933
104963
S421
Q
K
Y
S
E
A
V
S
L
C
K
T
L
I
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001121709
662
74613
V178
A
S
R
L
D
T
W
V
F
D
E
V
K
D
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192083
529
59421
K45
T
P
D
E
P
P
A
K
R
L
V
L
F
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_186787
993
112037
K467
K
S
Y
E
A
A
M
K
L
A
V
D
L
R
N
Baker's Yeast
Sacchar. cerevisiae
P36051
919
105675
Q427
E
G
E
N
Y
L
E
Q
E
A
I
T
L
T
E
Red Bread Mold
Neurospora crassa
Q7SAP1
996
110539
E438
G
R
Y
E
E
A
I
E
E
S
A
A
L
M
K
Conservation
Percent
Protein Identity:
100
99.3
N.A.
80.9
N.A.
87.3
87.2
N.A.
72.8
71.4
N.A.
44.4
N.A.
N.A.
N.A.
N.A.
35.3
Protein Similarity:
100
99.4
N.A.
86.3
N.A.
92.3
93.2
N.A.
84
83.8
N.A.
58.1
N.A.
N.A.
N.A.
N.A.
44.4
P-Site Identity:
100
100
N.A.
80
N.A.
80
73.3
N.A.
13.3
60
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
86.6
N.A.
86.6
86.6
N.A.
26.6
80
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.6
38.5
40.3
Protein Similarity:
N.A.
N.A.
N.A.
56.7
59.5
57.2
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
20
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
9
34
9
0
0
17
9
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
50
0
0
0
0
0
% C
% Asp:
0
0
9
42
17
0
0
0
0
9
0
9
0
9
17
% D
% Glu:
25
0
9
25
50
0
17
9
17
0
25
42
9
0
9
% E
% Phe:
0
0
42
0
0
0
0
0
9
0
0
0
9
0
9
% F
% Gly:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% H
% Ile:
0
0
0
0
0
0
9
9
9
0
9
0
0
50
0
% I
% Lys:
9
50
0
0
0
0
0
17
0
0
34
0
9
9
9
% K
% Leu:
9
0
0
9
0
9
0
0
59
9
0
17
75
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
17
% N
% Pro:
0
9
0
0
9
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
9
0
0
0
0
0
9
0
0
0
0
0
0
9
% Q
% Arg:
25
9
9
0
0
0
0
0
9
0
0
0
0
9
0
% R
% Ser:
0
17
0
17
0
0
0
50
0
9
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
9
0
0
0
0
0
17
0
9
9
% T
% Val:
0
0
0
0
0
42
50
9
0
9
25
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
34
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _