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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGN All Species: 24.55
Human Site: T670 Identified Species: 49.09
UniProt: O95427 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95427 NP_036459.1 931 105810 T670 S M Y V V Y S T Q S S L L R K
Chimpanzee Pan troglodytes XP_512161 931 105786 T670 S M Y V V Y S T Q S S L L R K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533387 987 112230 T726 S M Y V V Y S T H H S L L K K
Cat Felis silvestris
Mouse Mus musculus Q9R1S3 931 105027 T670 S M Y V V Y S T H H S L L K K
Rat Rattus norvegicus NP_001094054 931 104957 T670 S M Y V V Y S T H H S L L K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505836 960 108183 T699 S T Y I V S S T H S S L L L K
Chicken Gallus gallus XP_418994 933 104963 T672 S T Y V V S S T H N S L K N K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001121709 662 74613 A417 Q K G R F D E A I V Y C K D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001192083 529 59421 L284 P D E T L T P L L A W G A G V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_186787 993 112037 S730 S S V M V F L S T K H R T Q N
Baker's Yeast Sacchar. cerevisiae P36051 919 105675 H672 A A M L A V T H R S V I S L Q
Red Bread Mold Neurospora crassa Q7SAP1 996 110539 L704 T R S S A L S L Q A K Q G L P
Conservation
Percent
Protein Identity: 100 99.3 N.A. 80.9 N.A. 87.3 87.2 N.A. 72.8 71.4 N.A. 44.4 N.A. N.A. N.A. N.A. 35.3
Protein Similarity: 100 99.4 N.A. 86.3 N.A. 92.3 93.2 N.A. 84 83.8 N.A. 58.1 N.A. N.A. N.A. N.A. 44.4
P-Site Identity: 100 100 N.A. 80 N.A. 80 80 N.A. 66.6 60 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 N.A. 86.6 N.A. 86.6 86.6 N.A. 73.3 66.6 N.A. 0 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 37.6 38.5 40.3
Protein Similarity: N.A. N.A. N.A. 56.7 59.5 57.2
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. 40 46.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 17 0 0 9 0 17 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 9 0 0 0 9 0 0 0 0 0 0 0 9 0 % D
% Glu: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 0 0 0 0 0 0 0 9 9 9 0 % G
% His: 0 0 0 0 0 0 0 9 42 25 9 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 0 9 0 0 9 0 0 0 % I
% Lys: 0 9 0 0 0 0 0 0 0 9 9 0 17 25 59 % K
% Leu: 0 0 0 9 9 9 9 17 9 0 0 59 50 25 9 % L
% Met: 0 42 9 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 9 % N
% Pro: 9 0 0 0 0 0 9 0 0 0 0 0 0 0 9 % P
% Gln: 9 0 0 0 0 0 0 0 25 0 0 9 0 9 9 % Q
% Arg: 0 9 0 9 0 0 0 0 9 0 0 9 0 17 0 % R
% Ser: 67 9 9 9 0 17 67 9 0 34 59 0 9 0 0 % S
% Thr: 9 17 0 9 0 9 9 59 9 0 0 0 9 0 0 % T
% Val: 0 0 9 50 67 9 0 0 0 9 9 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 59 0 0 42 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _