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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIGN
All Species:
23.33
Human Site:
Y435
Identified Species:
46.67
UniProt:
O95427
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95427
NP_036459.1
931
105810
Y435
A
L
K
G
L
S
Y
Y
H
T
Y
D
R
F
F
Chimpanzee
Pan troglodytes
XP_512161
931
105786
Y435
A
L
K
G
L
S
Y
Y
H
T
Y
D
R
F
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533387
987
112230
Y491
A
L
K
G
L
S
Y
Y
H
T
Y
D
R
F
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1S3
931
105027
Y435
A
L
R
G
L
S
Y
Y
H
T
Y
D
R
L
F
Rat
Rattus norvegicus
NP_001094054
931
104957
Y435
A
L
R
G
L
S
Y
Y
H
T
Y
D
R
L
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505836
960
108183
L463
S
M
A
Q
K
L
A
L
D
C
F
K
Y
P
K
Chicken
Gallus gallus
XP_418994
933
104963
Y437
A
L
K
G
L
S
Y
Y
H
T
Y
D
R
L
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001121709
662
74613
T194
T
A
A
K
S
N
E
T
L
L
K
K
L
H
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192083
529
59421
Y61
G
L
R
A
D
K
L
Y
E
L
K
E
D
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_186787
993
112037
F483
S
L
E
G
L
H
Y
F
Q
T
Y
D
W
L
M
Baker's Yeast
Sacchar. cerevisiae
P36051
919
105675
G443
L
M
Q
I
T
L
E
G
L
H
Y
L
T
T
Y
Red Bread Mold
Neurospora crassa
Q7SAP1
996
110539
L454
G
L
G
G
L
R
Y
L
Q
T
Y
D
W
L
F
Conservation
Percent
Protein Identity:
100
99.3
N.A.
80.9
N.A.
87.3
87.2
N.A.
72.8
71.4
N.A.
44.4
N.A.
N.A.
N.A.
N.A.
35.3
Protein Similarity:
100
99.4
N.A.
86.3
N.A.
92.3
93.2
N.A.
84
83.8
N.A.
58.1
N.A.
N.A.
N.A.
N.A.
44.4
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
86.6
N.A.
0
93.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
20
93.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.6
38.5
40.3
Protein Similarity:
N.A.
N.A.
N.A.
56.7
59.5
57.2
P-Site Identity:
N.A.
N.A.
N.A.
46.6
6.6
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
26.6
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
9
17
9
0
0
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
9
0
0
67
9
0
0
% D
% Glu:
0
0
9
0
0
0
17
0
9
0
0
9
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
9
0
0
25
59
% F
% Gly:
17
0
9
67
0
0
0
9
0
0
0
0
0
9
0
% G
% His:
0
0
0
0
0
9
0
0
50
9
0
0
0
9
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
34
9
9
9
0
0
0
0
17
17
0
0
9
% K
% Leu:
9
75
0
0
67
17
9
17
17
17
0
9
9
42
0
% L
% Met:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
9
9
0
0
0
0
17
0
0
0
0
0
0
% Q
% Arg:
0
0
25
0
0
9
0
0
0
0
0
0
50
0
0
% R
% Ser:
17
0
0
0
9
50
0
0
0
0
0
0
0
0
0
% S
% Thr:
9
0
0
0
9
0
0
9
0
67
0
0
9
9
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% W
% Tyr:
0
0
0
0
0
0
67
59
0
0
75
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _