KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPLN
All Species:
12.73
Human Site:
S1212
Identified Species:
31.11
UniProt:
O95428
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95428
NP_775733.3
1278
137700
S1212
Y
Q
G
S
Q
A
V
S
R
S
T
E
V
K
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088864
1244
134167
S1178
Y
Q
G
S
Q
A
V
S
R
S
T
E
V
K
V
Dog
Lupus familis
XP_547891
1189
127952
E1143
Q
P
R
D
L
R
R
E
C
V
D
Q
P
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPX2
1280
138805
S1212
F
R
G
S
Q
A
V
S
R
S
T
E
V
K
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426430
1196
131476
T1140
L
R
S
R
P
S
T
T
V
N
H
V
V
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919035
930
101902
C885
G
Q
F
S
S
S
D
C
V
D
Q
P
E
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q868Z9
2898
313016
N2834
S
N
A
Y
T
Y
A
N
G
E
A
N
V
S
I
Honey Bee
Apis mellifera
XP_396472
2807
307624
S2732
S
N
D
Y
S
S
A
S
A
M
V
D
I
Q
V
Nematode Worm
Caenorhab. elegans
O76840
2167
237582
E2062
G
Q
D
S
T
M
S
E
G
V
E
V
V
I
K
Sea Urchin
Strong. purpuratus
XP_001182864
608
67786
P563
P
W
E
K
C
S
R
P
C
G
E
G
S
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
91.8
72.1
N.A.
74.5
N.A.
N.A.
N.A.
51.2
N.A.
33.4
N.A.
20.3
20.9
22.5
21.7
Protein Similarity:
100
N.A.
93
78
N.A.
82.3
N.A.
N.A.
N.A.
66.1
N.A.
45.6
N.A.
28.3
29.4
32.7
31
P-Site Identity:
100
N.A.
100
0
N.A.
86.6
N.A.
N.A.
N.A.
6.6
N.A.
13.3
N.A.
6.6
13.3
20
0
P-Site Similarity:
100
N.A.
100
20
N.A.
100
N.A.
N.A.
N.A.
40
N.A.
20
N.A.
20
40
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
30
20
0
10
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
10
20
0
0
0
0
0
0
% C
% Asp:
0
0
20
10
0
0
10
0
0
10
10
10
0
10
0
% D
% Glu:
0
0
10
0
0
0
0
20
0
10
20
30
10
10
0
% E
% Phe:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
0
30
0
0
0
0
0
20
10
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
10
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
30
10
% K
% Leu:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
20
% L
% Met:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
20
0
0
0
0
0
10
0
10
0
10
0
0
0
% N
% Pro:
10
10
0
0
10
0
0
10
0
0
0
10
10
0
0
% P
% Gln:
10
40
0
0
30
0
0
0
0
0
10
10
0
10
0
% Q
% Arg:
0
20
10
10
0
10
20
0
30
0
0
0
0
10
0
% R
% Ser:
20
0
10
50
20
40
10
40
0
30
0
0
10
10
0
% S
% Thr:
0
0
0
0
20
0
10
10
0
0
30
0
0
0
10
% T
% Val:
0
0
0
0
0
0
30
0
20
20
10
20
60
0
40
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
20
0
0
20
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _