KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPLN
All Species:
16.36
Human Site:
T139
Identified Species:
40
UniProt:
O95428
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95428
NP_775733.3
1278
137700
T139
R
E
A
V
V
D
G
T
P
C
E
P
G
K
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088864
1244
134167
K130
K
G
E
N
F
Y
Y
K
H
R
E
A
V
V
D
Dog
Lupus familis
XP_547891
1189
127952
N130
N
C
I
P
K
G
E
N
F
Y
Y
K
H
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPX2
1280
138805
T140
K
D
A
V
V
D
G
T
P
C
E
P
G
Q
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426430
1196
131476
T125
K
E
T
V
I
D
G
T
T
C
E
P
G
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919035
930
101902
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q868Z9
2898
313016
T170
R
E
K
V
V
D
G
T
R
C
N
D
K
D
L
Honey Bee
Apis mellifera
XP_396472
2807
307624
T161
K
L
M
V
I
D
G
T
P
C
E
V
E
K
N
Nematode Worm
Caenorhab. elegans
O76840
2167
237582
T180
A
D
K
V
V
D
G
T
K
C
D
S
K
S
N
Sea Urchin
Strong. purpuratus
XP_001182864
608
67786
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
91.8
72.1
N.A.
74.5
N.A.
N.A.
N.A.
51.2
N.A.
33.4
N.A.
20.3
20.9
22.5
21.7
Protein Similarity:
100
N.A.
93
78
N.A.
82.3
N.A.
N.A.
N.A.
66.1
N.A.
45.6
N.A.
28.3
29.4
32.7
31
P-Site Identity:
100
N.A.
6.6
0
N.A.
80
N.A.
N.A.
N.A.
73.3
N.A.
0
N.A.
53.3
53.3
40
0
P-Site Similarity:
100
N.A.
13.3
6.6
N.A.
100
N.A.
N.A.
N.A.
86.6
N.A.
0
N.A.
53.3
66.6
53.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
20
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
60
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
60
0
0
0
0
10
10
0
10
10
% D
% Glu:
0
30
10
0
0
0
10
0
0
0
50
0
10
0
10
% E
% Phe:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
10
60
0
0
0
0
0
30
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
20
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
40
0
20
0
10
0
0
10
10
0
0
10
20
30
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
0
0
10
0
0
10
0
0
0
20
% N
% Pro:
0
0
0
10
0
0
0
0
30
0
0
30
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
20
0
0
0
0
0
0
0
10
10
0
0
0
10
30
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% S
% Thr:
0
0
10
0
0
0
0
60
10
0
0
0
0
0
0
% T
% Val:
0
0
0
60
40
0
0
0
0
0
0
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
0
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _