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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAPLN
All Species:
7.88
Human Site:
T504
Identified Species:
19.26
UniProt:
O95428
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95428
NP_775733.3
1278
137700
T504
S
K
S
C
S
S
G
T
R
R
R
Q
V
I
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001088864
1244
134167
S472
X
X
X
X
C
S
K
S
C
S
S
G
T
R
R
Dog
Lupus familis
XP_547891
1189
127952
S470
S
P
R
D
P
W
M
S
L
G
P
Q
G
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPX2
1280
138805
S500
S
W
S
L
C
S
K
S
C
G
S
G
I
R
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426430
1196
131476
Q465
N
S
G
I
R
T
R
Q
V
I
C
A
D
G
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919035
930
101902
Y217
S
K
E
C
G
S
G
Y
Q
S
R
L
V
F
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q868Z9
2898
313016
P837
S
D
A
T
S
E
A
P
A
S
S
V
S
D
S
Honey Bee
Apis mellifera
XP_396472
2807
307624
T910
S
E
S
E
S
T
V
T
E
Q
E
M
T
E
E
Nematode Worm
Caenorhab. elegans
O76840
2167
237582
E790
S
V
T
N
E
N
G
E
A
V
D
V
E
C
A
Sea Urchin
Strong. purpuratus
XP_001182864
608
67786
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
91.8
72.1
N.A.
74.5
N.A.
N.A.
N.A.
51.2
N.A.
33.4
N.A.
20.3
20.9
22.5
21.7
Protein Similarity:
100
N.A.
93
78
N.A.
82.3
N.A.
N.A.
N.A.
66.1
N.A.
45.6
N.A.
28.3
29.4
32.7
31
P-Site Identity:
100
N.A.
6.6
13.3
N.A.
20
N.A.
N.A.
N.A.
0
N.A.
53.3
N.A.
13.3
26.6
13.3
0
P-Site Similarity:
100
N.A.
13.3
20
N.A.
33.3
N.A.
N.A.
N.A.
13.3
N.A.
60
N.A.
20
46.6
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
10
0
20
0
0
10
0
10
10
% A
% Cys:
0
0
0
20
20
0
0
0
20
0
10
0
0
10
20
% C
% Asp:
0
10
0
10
0
0
0
0
0
0
10
0
10
10
10
% D
% Glu:
0
10
10
10
10
10
0
10
10
0
10
0
10
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
10
0
10
0
30
0
0
20
0
20
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
10
0
0
10
10
0
% I
% Lys:
0
20
0
0
0
0
20
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
0
0
0
10
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% M
% Asn:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
10
0
0
10
0
0
10
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
10
10
10
0
20
0
0
0
% Q
% Arg:
0
0
10
0
10
0
10
0
10
10
20
0
0
20
20
% R
% Ser:
70
10
30
0
30
40
0
30
0
30
30
0
10
0
10
% S
% Thr:
0
0
10
10
0
20
0
20
0
0
0
0
20
0
0
% T
% Val:
0
10
0
0
0
0
10
0
10
10
0
20
20
0
0
% V
% Trp:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _