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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCA5L
All Species:
15.45
Human Site:
Y524
Identified Species:
42.5
UniProt:
O95447
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95447
NP_689718.1
670
76505
Y524
P
L
R
Q
R
R
H
Y
S
F
T
E
A
T
E
Chimpanzee
Pan troglodytes
XP_531564
670
76442
Y524
P
L
R
Q
R
R
H
Y
S
F
T
E
A
T
E
Rhesus Macaque
Macaca mulatta
XP_001108383
670
76466
Y524
P
L
R
Q
R
R
H
Y
S
F
T
E
A
T
E
Dog
Lupus familis
XP_535594
665
74260
K520
K
A
P
L
R
P
R
K
H
Y
S
F
T
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0X0
741
82480
R590
D
V
E
P
G
R
G
R
R
K
T
P
R
K
H
Rat
Rattus norvegicus
Q5U2Y9
727
82591
P502
F
E
S
K
L
Y
S
P
D
R
S
L
R
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510840
727
82430
Y569
P
I
K
Q
R
K
Y
Y
S
F
T
E
A
I
E
Chicken
Gallus gallus
XP_419870
683
79593
G537
E
D
A
T
R
A
H
G
Q
K
Q
R
N
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A3KNA5
1129
129722
S658
E
S
L
E
K
R
Y
S
N
E
Q
E
R
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
95.6
69.6
N.A.
55.2
27.6
N.A.
49.5
28.2
N.A.
21.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
97
77.6
N.A.
66.9
47.5
N.A.
65.3
50.2
N.A.
36.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
13.3
0
N.A.
66.6
13.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
20
13.3
N.A.
93.3
13.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
0
12
0
0
0
0
0
0
45
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
0
0
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
23
12
12
12
0
0
0
0
0
12
0
56
0
12
45
% E
% Phe:
12
0
0
0
0
0
0
0
0
45
0
12
0
0
0
% F
% Gly:
0
0
0
0
12
0
12
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
45
0
12
0
0
0
0
0
12
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
12
0
% I
% Lys:
12
0
12
12
12
12
0
12
0
23
0
0
0
12
12
% K
% Leu:
0
34
12
12
12
0
0
0
0
0
0
12
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
0
0
12
0
0
% N
% Pro:
45
0
12
12
0
12
0
12
0
0
0
12
0
12
0
% P
% Gln:
0
0
0
45
0
0
0
0
12
0
23
0
0
0
0
% Q
% Arg:
0
0
34
0
67
56
12
12
12
12
0
12
34
0
12
% R
% Ser:
0
12
12
0
0
0
12
12
45
0
23
0
0
0
0
% S
% Thr:
0
0
0
12
0
0
0
0
0
0
56
0
12
34
0
% T
% Val:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
23
45
0
12
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _