KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS2
All Species:
10
Human Site:
T145
Identified Species:
27.5
UniProt:
O95450
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95450
NP_055059.2
1211
134755
T145
E
W
Q
G
E
K
G
T
T
R
V
E
P
L
L
Chimpanzee
Pan troglodytes
XP_518147
1209
134247
T143
E
W
Q
G
E
K
G
T
T
R
V
E
P
L
L
Rhesus Macaque
Macaca mulatta
XP_001102920
1252
138512
T186
E
W
Q
G
E
T
G
T
T
R
V
E
P
L
L
Dog
Lupus familis
XP_848937
1210
134554
A142
E
W
Q
S
E
S
G
A
T
R
V
E
P
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C9W3
1213
135281
D144
E
W
Q
G
E
T
G
D
T
R
V
E
P
L
L
Rat
Rattus norvegicus
Q1EHB3
1595
175796
T117
H
I
Q
T
S
V
P
T
C
H
L
L
G
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505715
1189
133383
V127
E
W
Q
E
D
S
N
V
T
Y
V
E
P
L
L
Chicken
Gallus gallus
XP_414611
1559
174471
E485
E
W
Q
E
D
S
D
E
T
H
I
E
P
L
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700384
1270
143664
Q124
E
W
L
E
D
D
N
Q
T
H
S
E
P
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
92.8
90.6
N.A.
88.6
26.2
N.A.
70.4
59.5
N.A.
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
94.5
94.8
N.A.
92.9
39
N.A.
78.4
66.5
N.A.
67.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
86.6
13.3
N.A.
60
46.6
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
86.6
26.6
N.A.
66.6
60
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
34
12
12
12
0
0
0
0
0
12
0
% D
% Glu:
89
0
0
34
56
0
0
12
0
0
0
89
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
45
0
0
56
0
0
0
0
0
12
0
0
% G
% His:
12
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
12
0
0
0
0
0
0
0
12
12
0
89
78
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
0
0
0
0
89
0
0
% P
% Gln:
0
0
89
0
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
56
0
0
0
0
0
% R
% Ser:
0
0
0
12
12
34
0
0
0
0
12
0
0
0
0
% S
% Thr:
0
0
0
12
0
23
0
45
89
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
12
0
12
0
0
67
0
0
0
12
% V
% Trp:
0
89
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _