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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GJB6
All Species:
13.33
Human Site:
S222
Identified Species:
32.59
UniProt:
O95452
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95452
NP_001103689.1
261
30387
S222
L
K
V
C
F
R
R
S
K
R
A
Q
T
Q
K
Chimpanzee
Pan troglodytes
XP_001145895
209
24152
K171
F
V
S
R
P
T
E
K
T
V
F
T
V
F
M
Rhesus Macaque
Macaca mulatta
Q8MIT8
226
26206
K188
F
V
S
R
P
T
E
K
T
V
F
T
V
F
M
Dog
Lupus familis
XP_543177
226
26241
K188
F
V
S
R
P
T
E
K
T
V
F
T
V
F
M
Cat
Felis silvestris
Mouse
Mus musculus
P70689
261
30348
S222
L
K
L
C
F
R
R
S
K
R
T
Q
A
Q
R
Rat
Rattus norvegicus
P21994
226
26433
K188
F
I
S
R
P
T
E
K
T
V
F
T
V
F
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516391
261
29978
S222
M
K
V
C
F
R
Q
S
K
R
A
Q
N
Q
G
Chicken
Gallus gallus
O93533
263
30905
S222
T
K
F
F
L
R
R
S
R
K
A
G
N
Q
K
Frog
Xenopus laevis
P08983
264
29977
A221
A
Q
A
C
T
R
R
A
R
R
H
R
D
S
G
Zebra Danio
Brachydanio rerio
NP_997990
267
30305
S224
V
K
A
L
L
R
C
S
A
R
A
K
G
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.4
66.6
66.6
N.A.
95.4
65.9
N.A.
85.4
73
53.7
56.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72.4
77.3
77
N.A.
97.6
76.2
N.A.
92.7
86.6
71.9
73.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
0
N.A.
73.3
0
N.A.
73.3
46.6
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
0
0
N.A.
86.6
0
N.A.
86.6
60
53.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
20
0
0
0
0
10
10
0
40
0
10
0
0
% A
% Cys:
0
0
0
40
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
40
0
0
0
0
0
0
0
0
% E
% Phe:
40
0
10
10
30
0
0
0
0
0
40
0
0
40
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
50
0
0
0
0
0
40
30
10
0
10
0
0
20
% K
% Leu:
20
0
10
10
20
0
0
0
0
0
0
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
40
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
20
0
0
% N
% Pro:
0
0
0
0
40
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
10
0
0
0
0
30
0
40
0
% Q
% Arg:
0
0
0
40
0
60
40
0
20
50
0
10
0
10
20
% R
% Ser:
0
0
40
0
0
0
0
50
0
0
0
0
0
10
0
% S
% Thr:
10
0
0
0
10
40
0
0
40
0
10
40
10
0
0
% T
% Val:
10
30
20
0
0
0
0
0
0
40
0
0
40
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _