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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARN All Species: 22.42
Human Site: S35 Identified Species: 44.85
UniProt: O95453 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95453 NP_001127949.1 639 73451 S35 D G E F S G I S D G P S V S A
Chimpanzee Pan troglodytes XP_510832 934 103856 S330 D G E F S G I S D G P S V S A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536966 638 73370 S35 D G E F S G I S D G P S V T A
Cat Felis silvestris
Mouse Mus musculus Q8VDG3 624 71541 S35 D G E F S G I S D G P S V T A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505796 443 50245
Chicken Gallus gallus NP_001025800 574 66359
Frog Xenopus laevis Q90ZA1 631 72827 S35 D G E F S G I S D G P S V S T
Zebra Danio Brachydanio rerio Q7ZU92 660 75243 S35 D G E F T G I S D G P S V S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392167 576 66398
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785661 340 38396
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001169499 693 77507 G70 G L D L E M S G V T S A P W R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LG26 689 77992 G71 A I D L E M T G V T S A P W R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.3 N.A. 92.9 N.A. 86.8 N.A. N.A. 49.7 74.3 74.6 63.1 N.A. N.A. 38.8 N.A. 22.3
Protein Similarity: 100 68.3 N.A. 96.5 N.A. 92.4 N.A. N.A. 54.2 81.8 85.7 77.1 N.A. N.A. 60.2 N.A. 33.3
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 N.A. N.A. 0 0 93.3 93.3 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 N.A. N.A. 0 0 93.3 100 N.A. N.A. 0 N.A. 0
Percent
Protein Identity: N.A. 21.3 N.A. 20.4 N.A. N.A.
Protein Similarity: N.A. 38.8 N.A. 40.2 N.A. N.A.
P-Site Identity: N.A. 0 N.A. 0 N.A. N.A.
P-Site Similarity: N.A. 13.3 N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 0 0 0 0 17 0 0 42 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 50 0 17 0 0 0 0 0 50 0 0 0 0 0 0 % D
% Glu: 0 0 50 0 17 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 50 0 0 0 50 0 17 0 50 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 50 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 0 17 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 50 0 17 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % R
% Ser: 0 0 0 0 42 0 9 50 0 0 17 50 0 34 0 % S
% Thr: 0 0 0 0 9 0 9 0 0 17 0 0 0 17 9 % T
% Val: 0 0 0 0 0 0 0 0 17 0 0 0 50 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _