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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PARN All Species: 23.94
Human Site: S368 Identified Species: 47.88
UniProt: O95453 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95453 NP_001127949.1 639 73451 S368 E S A E G F P S Y D T A S E Q
Chimpanzee Pan troglodytes XP_510832 934 103856 S663 E S A E G F P S Y D T A S E Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536966 638 73370 S368 E S A E G F P S Y D T A T E Q
Cat Felis silvestris
Mouse Mus musculus Q8VDG3 624 71541 S361 E S A E G F P S Y D T A S E Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505796 443 50245 M184 K L F L M R I M D I P Y L N L
Chicken Gallus gallus NP_001025800 574 66359 L315 Y D T A S E Q L H E A G Y D A
Frog Xenopus laevis Q90ZA1 631 72827 S367 D S A E G F Q S Y N T A S E Q
Zebra Danio Brachydanio rerio Q7ZU92 660 75243 S366 E C P E G L Q S Y D T S T E Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392167 576 66398 Q317 K I I C H S Q Q F K E N I P S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785661 340 38396 Y81 K Q K K G Y G Y V A Y P F N L
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001169499 693 77507 S394 A D T R H L M S V N Q A V Q K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LG26 689 77992 I419 F S S L C P Q I E F S S R S S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.3 N.A. 92.9 N.A. 86.8 N.A. N.A. 49.7 74.3 74.6 63.1 N.A. N.A. 38.8 N.A. 22.3
Protein Similarity: 100 68.3 N.A. 96.5 N.A. 92.4 N.A. N.A. 54.2 81.8 85.7 77.1 N.A. N.A. 60.2 N.A. 33.3
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 N.A. N.A. 0 0 80 60 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 N.A. N.A. 6.6 20 93.3 73.3 N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: N.A. 21.3 N.A. 20.4 N.A. N.A.
Protein Similarity: N.A. 38.8 N.A. 40.2 N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 42 9 0 0 0 0 0 9 9 50 0 0 9 % A
% Cys: 0 9 0 9 9 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 17 0 0 0 0 0 0 9 42 0 0 0 9 0 % D
% Glu: 42 0 0 50 0 9 0 0 9 9 9 0 0 50 0 % E
% Phe: 9 0 9 0 0 42 0 0 9 9 0 0 9 0 0 % F
% Gly: 0 0 0 0 59 0 9 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 0 17 0 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 9 9 0 0 0 9 9 0 9 0 0 9 0 0 % I
% Lys: 25 0 9 9 0 0 0 0 0 9 0 0 0 0 9 % K
% Leu: 0 9 0 17 0 17 0 9 0 0 0 0 9 0 17 % L
% Met: 0 0 0 0 9 0 9 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 17 0 9 0 17 0 % N
% Pro: 0 0 9 0 0 9 34 0 0 0 9 9 0 9 0 % P
% Gln: 0 9 0 0 0 0 42 9 0 0 9 0 0 9 50 % Q
% Arg: 0 0 0 9 0 9 0 0 0 0 0 0 9 0 0 % R
% Ser: 0 50 9 0 9 9 0 59 0 0 9 17 34 9 17 % S
% Thr: 0 0 17 0 0 0 0 0 0 0 50 0 17 0 0 % T
% Val: 0 0 0 0 0 0 0 0 17 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 9 0 9 50 0 9 9 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _