Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TGDS All Species: 33.03
Human Site: S281 Identified Species: 60.56
UniProt: O95455 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95455 NP_055120.1 350 40214 S281 Q L I K E T N S E S E M E N W
Chimpanzee Pan troglodytes XP_522697 350 40132 S281 Q L I K E T N S E S E M E N W
Rhesus Macaque Macaca mulatta XP_001083495 350 40133 S281 Q L I K E T N S E S E M E N W
Dog Lupus familis XP_542640 514 57720 S440 Q L I K E T S S E S E M E T W
Cat Felis silvestris
Mouse Mus musculus Q8VDR7 355 40580 S281 Q L I K E T N S E S E T E S W
Rat Rattus norvegicus Q5PQX0 420 47520 S346 K N L V G S G S E I Q F L S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512139 406 46234 T331 Q L I K E T S T E S E T E N W
Chicken Gallus gallus XP_416988 357 41177 S278 H L I K K T S S E S E M E H W
Frog Xenopus laevis NP_001088301 351 40134 S280 Q T I K N T E S E S E L N N W
Zebra Danio Brachydanio rerio NP_956111 274 30744 Y223 L Q S R H F L Y V S D V T D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002330754 660 74671 E278 K L Y G L D P E K S I N Y V Q
Maize Zea mays NP_001130297 676 76169 N281 K D V C R L F N L E P D K V I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SYM5 669 75353 P433 Q D I Q S V K P T H V F N S A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 98.8 65.7 N.A. 89.5 22.1 N.A. 78.3 83.1 72.9 49.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 99.1 67.1 N.A. 94 39.2 N.A. 83.2 90.1 87.4 61.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 86.6 13.3 N.A. 80 73.3 66.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 46.6 N.A. 93.3 93.3 73.3 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 26.5 25 N.A. 24.9 N.A. N.A.
Protein Similarity: 38 35.9 N.A. 35.8 N.A. N.A.
P-Site Identity: 13.3 0 N.A. 13.3 N.A. N.A.
P-Site Similarity: 26.6 26.6 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 16 0 0 0 8 0 0 0 0 8 8 0 8 0 % D
% Glu: 0 0 0 0 47 0 8 8 70 8 62 0 54 0 8 % E
% Phe: 0 0 0 0 0 8 8 0 0 0 0 16 0 0 0 % F
% Gly: 0 0 0 8 8 0 8 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 8 0 0 0 0 8 0 0 0 8 0 % H
% Ile: 0 0 70 0 0 0 0 0 0 8 8 0 0 0 8 % I
% Lys: 24 0 0 62 8 0 8 0 8 0 0 0 8 0 0 % K
% Leu: 8 62 8 0 8 8 8 0 8 0 0 8 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 39 0 0 0 % M
% Asn: 0 8 0 0 8 0 31 8 0 0 0 8 16 39 0 % N
% Pro: 0 0 0 0 0 0 8 8 0 0 8 0 0 0 0 % P
% Gln: 62 8 0 8 0 0 0 0 0 0 8 0 0 0 8 % Q
% Arg: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 8 0 8 8 24 62 0 77 0 0 0 24 0 % S
% Thr: 0 8 0 0 0 62 0 8 8 0 0 16 8 8 0 % T
% Val: 0 0 8 8 0 8 0 0 8 0 8 8 0 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 62 % W
% Tyr: 0 0 8 0 0 0 0 8 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _