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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGDS
All Species:
30
Human Site:
S65
Identified Species:
55
UniProt:
O95455
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95455
NP_055120.1
350
40214
S65
L
K
N
L
E
T
I
S
N
K
Q
N
Y
K
F
Chimpanzee
Pan troglodytes
XP_522697
350
40132
S65
L
K
N
L
E
T
I
S
N
K
Q
N
Y
K
F
Rhesus Macaque
Macaca mulatta
XP_001083495
350
40133
S65
L
K
N
L
E
T
I
S
N
K
Q
N
Y
K
F
Dog
Lupus familis
XP_542640
514
57720
S224
L
K
N
L
E
T
I
S
N
K
Q
N
Y
K
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDR7
355
40580
S65
L
K
N
L
E
P
V
S
N
K
Q
N
Y
K
F
Rat
Rattus norvegicus
Q5PQX0
420
47520
E130
T
G
R
K
R
N
V
E
H
W
I
G
H
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512139
406
46234
S115
L
K
N
L
E
T
I
S
N
K
Q
N
Y
K
F
Chicken
Gallus gallus
XP_416988
357
41177
S62
L
K
N
L
E
T
V
S
E
K
E
N
Y
K
F
Frog
Xenopus laevis
NP_001088301
351
40134
H64
N
L
E
S
V
S
S
H
P
N
Y
T
F
I
Q
Zebra Danio
Brachydanio rerio
NP_956111
274
30744
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002330754
660
74671
N62
A
T
C
R
G
S
P
N
F
K
F
V
K
G
D
Maize
Zea mays
NP_001130297
676
76169
S65
L
K
N
L
L
P
V
S
S
S
P
N
F
K
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SYM5
669
75353
G217
G
Q
V
L
P
I
H
G
D
G
S
N
V
R
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.8
65.7
N.A.
89.5
22.1
N.A.
78.3
83.1
72.9
49.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
99.1
67.1
N.A.
94
39.2
N.A.
83.2
90.1
87.4
61.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
0
N.A.
100
80
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
100
93.3
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
26.5
25
N.A.
24.9
N.A.
N.A.
Protein Similarity:
38
35.9
N.A.
35.8
N.A.
N.A.
P-Site Identity:
6.6
53.3
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
73.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% D
% Glu:
0
0
8
0
54
0
0
8
8
0
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
8
0
16
0
62
% F
% Gly:
8
8
0
0
8
0
0
8
0
8
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
8
8
8
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
39
0
0
0
8
0
0
8
0
% I
% Lys:
0
62
0
8
0
0
0
0
0
62
0
0
8
62
0
% K
% Leu:
62
8
0
70
8
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
62
0
0
8
0
8
47
8
0
70
0
0
8
% N
% Pro:
0
0
0
0
8
16
8
0
8
0
8
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
47
0
0
0
8
% Q
% Arg:
0
0
8
8
8
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
0
0
8
0
16
8
62
8
8
8
0
0
0
8
% S
% Thr:
8
8
0
0
0
47
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
8
0
8
0
31
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
54
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _