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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGDS
All Species:
33.03
Human Site:
T142
Identified Species:
60.56
UniProt:
O95455
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95455
NP_055120.1
350
40214
T142
E
K
F
I
Y
V
S
T
D
E
V
Y
G
G
S
Chimpanzee
Pan troglodytes
XP_522697
350
40132
T142
E
K
F
I
Y
V
S
T
D
E
V
Y
G
G
S
Rhesus Macaque
Macaca mulatta
XP_001083495
350
40133
T142
E
K
F
I
Y
V
S
T
D
E
V
Y
G
G
S
Dog
Lupus familis
XP_542640
514
57720
T301
E
K
F
I
Y
V
S
T
D
E
V
Y
G
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDR7
355
40580
T142
E
K
F
I
Y
V
S
T
D
E
V
Y
G
G
S
Rat
Rattus norvegicus
Q5PQX0
420
47520
G207
A
S
T
S
E
V
Y
G
D
P
E
V
H
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512139
406
46234
T192
E
K
F
I
Y
V
S
T
D
E
V
Y
G
G
S
Chicken
Gallus gallus
XP_416988
357
41177
T139
E
K
F
V
Y
V
S
T
D
E
V
Y
G
G
S
Frog
Xenopus laevis
NP_001088301
351
40134
T141
E
K
F
V
Y
I
S
T
D
E
V
Y
G
G
S
Zebra Danio
Brachydanio rerio
NP_956111
274
30744
V84
S
T
E
H
I
D
V
V
F
H
C
A
A
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002330754
660
74671
V139
I
H
V
S
T
D
E
V
Y
G
E
T
D
M
E
Maize
Zea mays
NP_001130297
676
76169
S142
I
K
R
F
I
H
V
S
T
D
E
V
Y
G
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SYM5
669
75353
D294
D
Q
R
Y
F
L
D
D
Q
K
L
K
K
L
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.8
65.7
N.A.
89.5
22.1
N.A.
78.3
83.1
72.9
49.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
99.1
67.1
N.A.
94
39.2
N.A.
83.2
90.1
87.4
61.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
100
93.3
86.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
100
100
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
26.5
25
N.A.
24.9
N.A.
N.A.
Protein Similarity:
38
35.9
N.A.
35.8
N.A.
N.A.
P-Site Identity:
0
13.3
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
26.6
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
0
0
0
0
16
8
8
70
8
0
0
8
0
0
% D
% Glu:
62
0
8
0
8
0
8
0
0
62
24
0
0
8
16
% E
% Phe:
0
0
62
8
8
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
8
0
0
62
70
8
% G
% His:
0
8
0
8
0
8
0
0
0
8
0
0
8
0
0
% H
% Ile:
16
0
0
47
16
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
70
0
0
0
0
0
0
0
8
0
8
8
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
0
0
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% P
% Gln:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
8
% Q
% Arg:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
0
16
0
0
62
8
0
0
0
0
0
0
62
% S
% Thr:
0
8
8
0
8
0
0
62
8
0
0
8
0
0
8
% T
% Val:
0
0
8
16
0
62
16
16
0
0
62
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
62
0
8
0
8
0
0
62
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _