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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGDS
All Species:
30.3
Human Site:
Y184
Identified Species:
55.56
UniProt:
O95455
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95455
NP_055120.1
350
40214
Y184
V
Q
S
Y
W
E
Q
Y
K
F
P
V
V
I
T
Chimpanzee
Pan troglodytes
XP_522697
350
40132
Y184
V
Q
S
Y
W
E
Q
Y
K
F
P
V
V
I
T
Rhesus Macaque
Macaca mulatta
XP_001083495
350
40133
Y184
V
Q
S
Y
W
E
R
Y
K
F
P
V
V
I
T
Dog
Lupus familis
XP_542640
514
57720
Y343
V
Q
S
Y
W
E
R
Y
K
F
P
A
V
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDR7
355
40580
Y184
V
Q
S
Y
W
E
R
Y
K
F
P
V
V
I
T
Rat
Rattus norvegicus
Q5PQX0
420
47520
E249
C
Y
A
Y
M
K
Q
E
G
V
E
V
R
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512139
406
46234
Y234
V
Q
S
Y
W
E
R
Y
K
F
P
V
V
I
T
Chicken
Gallus gallus
XP_416988
357
41177
Y181
V
Q
S
Y
W
E
R
Y
Q
F
P
V
V
I
T
Frog
Xenopus laevis
NP_001088301
351
40134
H183
V
L
S
F
W
E
R
H
K
F
P
V
V
I
T
Zebra Danio
Brachydanio rerio
NP_956111
274
30744
F126
L
E
A
S
V
Q
R
F
I
Y
I
S
T
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002330754
660
74671
Y181
V
M
A
Y
H
R
S
Y
G
L
P
I
I
T
T
Maize
Zea mays
NP_001130297
676
76169
Y184
A
E
M
L
V
M
A
Y
G
R
S
Y
G
L
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SYM5
669
75353
H336
V
S
G
A
L
L
P
H
P
R
M
L
M
M
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
98.8
65.7
N.A.
89.5
22.1
N.A.
78.3
83.1
72.9
49.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
99.1
67.1
N.A.
94
39.2
N.A.
83.2
90.1
87.4
61.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
20
N.A.
93.3
86.6
73.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
40
N.A.
100
100
93.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
26.5
25
N.A.
24.9
N.A.
N.A.
Protein Similarity:
38
35.9
N.A.
35.8
N.A.
N.A.
P-Site Identity:
33.3
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
53.3
20
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
24
8
0
0
8
0
0
0
0
8
0
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
16
0
0
0
62
0
8
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
8
0
0
0
8
0
62
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
24
0
0
0
8
0
0
% G
% His:
0
0
0
0
8
0
0
16
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
8
8
8
62
0
% I
% Lys:
0
0
0
0
0
8
0
0
54
0
0
0
0
0
0
% K
% Leu:
8
8
0
8
8
8
0
0
0
8
0
8
0
8
0
% L
% Met:
0
8
8
0
8
8
0
0
0
0
8
0
8
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
0
8
0
70
0
0
0
16
% P
% Gln:
0
54
0
0
0
8
24
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
54
0
0
16
0
0
8
0
0
% R
% Ser:
0
8
62
8
0
0
8
0
0
0
8
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
70
% T
% Val:
77
0
0
0
16
0
0
0
0
8
0
62
62
8
0
% V
% Trp:
0
0
0
0
62
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
70
0
0
0
70
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _