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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LARGE
All Species:
33.64
Human Site:
Y570
Identified Species:
67.27
UniProt:
O95461
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95461
NP_004728.1
756
88066
Y570
D
I
D
F
L
P
M
Y
G
L
Y
E
Y
L
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112944
756
88032
Y570
D
I
D
F
L
P
M
Y
G
L
Y
E
Y
L
R
Dog
Lupus familis
XP_531751
827
95704
Y641
D
I
D
F
L
P
M
Y
G
L
Y
E
Y
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1M7
756
87945
Y570
D
I
D
F
L
P
M
Y
G
L
Y
E
Y
L
R
Rat
Rattus norvegicus
Q6P7A1
690
79291
L513
A
S
I
E
Q
L
A
L
G
R
R
Q
R
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510588
766
89047
Y580
D
I
D
F
L
P
M
Y
G
L
Y
E
Y
L
R
Chicken
Gallus gallus
Q66PG3
756
88027
Y570
D
I
D
F
L
P
M
Y
G
L
Y
E
Y
L
R
Frog
Xenopus laevis
Q6PA90
723
83130
Y537
D
I
D
F
L
P
M
Y
G
L
Y
E
Y
L
R
Zebra Danio
Brachydanio rerio
Q66PG2
757
87655
Y571
D
I
D
F
L
P
M
Y
G
L
Y
E
Y
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624139
712
83352
S532
V
K
L
N
M
S
E
S
D
K
V
A
L
I
V
Nematode Worm
Caenorhab. elegans
Q21389
631
74506
Y454
D
F
V
V
L
G
D
Y
G
T
I
I
D
Q
T
Sea Urchin
Strong. purpuratus
XP_781563
562
65956
R385
Y
G
L
Y
D
Y
L
R
K
A
I
G
M
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
88.7
N.A.
97.7
60
N.A.
91.7
95.9
71.1
84.6
N.A.
N.A.
46.1
28.9
56.3
Protein Similarity:
100
N.A.
100
90.3
N.A.
99.2
74.5
N.A.
94.5
98.4
81.6
91.9
N.A.
N.A.
63
46.4
64.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
6.6
N.A.
100
100
100
100
N.A.
N.A.
0
26.6
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
100
100
100
100
N.A.
N.A.
13.3
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
9
0
0
9
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
75
0
67
0
9
0
9
0
9
0
0
0
9
0
9
% D
% Glu:
0
0
0
9
0
0
9
0
0
0
0
67
0
0
0
% E
% Phe:
0
9
0
67
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
9
0
0
84
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
67
9
0
0
0
0
0
0
0
17
9
0
9
0
% I
% Lys:
0
9
0
0
0
0
0
0
9
9
0
0
0
9
0
% K
% Leu:
0
0
17
0
75
9
9
9
0
67
0
0
9
75
0
% L
% Met:
0
0
0
0
9
0
67
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
9
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
9
0
9
9
0
9
0
67
% R
% Ser:
0
9
0
0
0
9
0
9
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% T
% Val:
9
0
9
9
0
0
0
0
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
9
0
75
0
0
67
0
67
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _