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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LARGE
All Species:
30.61
Human Site:
Y749
Identified Species:
61.21
UniProt:
O95461
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95461
NP_004728.1
756
88066
Y749
Y
G
F
A
A
L
K
Y
L
T
A
E
N
N
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112944
756
88032
Y749
Y
G
F
A
A
L
K
Y
L
T
A
E
N
N
S
Dog
Lupus familis
XP_531751
827
95704
Y820
Y
G
F
A
A
L
K
Y
L
T
A
E
N
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1M7
756
87945
Y749
Y
G
F
A
A
L
K
Y
L
T
A
E
N
N
S
Rat
Rattus norvegicus
Q6P7A1
690
79291
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510588
766
89047
Y759
Y
G
F
A
A
L
K
Y
L
T
A
E
N
N
S
Chicken
Gallus gallus
Q66PG3
756
88027
Y749
Y
G
F
A
A
L
K
Y
L
T
A
E
N
N
S
Frog
Xenopus laevis
Q6PA90
723
83130
Y716
Y
G
S
A
A
L
K
Y
L
T
A
E
R
N
R
Zebra Danio
Brachydanio rerio
Q66PG2
757
87655
Y750
Y
G
F
A
A
L
K
Y
M
T
V
D
N
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624139
712
83352
L705
M
T
K
D
E
R
I
L
K
S
V
E
T
K
K
Nematode Worm
Caenorhab. elegans
Q21389
631
74506
Sea Urchin
Strong. purpuratus
XP_781563
562
65956
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.8
88.7
N.A.
97.7
60
N.A.
91.7
95.9
71.1
84.6
N.A.
N.A.
46.1
28.9
56.3
Protein Similarity:
100
N.A.
100
90.3
N.A.
99.2
74.5
N.A.
94.5
98.4
81.6
91.9
N.A.
N.A.
63
46.4
64.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
0
N.A.
100
100
80
80
N.A.
N.A.
6.6
0
0
P-Site Similarity:
100
N.A.
100
100
N.A.
100
0
N.A.
100
100
80
93.3
N.A.
N.A.
13.3
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
67
67
0
0
0
0
0
59
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
0
0
67
0
0
0
% E
% Phe:
0
0
59
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
67
0
9
0
0
0
0
9
9
% K
% Leu:
0
0
0
0
0
67
0
9
59
0
0
0
0
0
0
% L
% Met:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
59
67
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
9
% R
% Ser:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
59
% S
% Thr:
0
9
0
0
0
0
0
0
0
67
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
67
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _