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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPL1
All Species:
17.58
Human Site:
S104
Identified Species:
24.17
UniProt:
O95470
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95470
NP_003892.2
568
63524
S104
D
D
I
S
K
N
M
S
F
L
K
V
D
K
E
Chimpanzee
Pan troglodytes
XP_521504
568
63517
S104
D
D
I
S
K
N
M
S
F
L
K
V
D
K
E
Rhesus Macaque
Macaca mulatta
XP_001106861
633
70448
S169
D
D
I
S
K
N
M
S
F
L
K
V
D
K
E
Dog
Lupus familis
XP_546150
568
63418
S104
D
D
I
S
K
N
M
S
F
L
K
V
D
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0X7
568
63659
P104
K
D
L
V
K
N
M
P
F
L
K
V
D
K
D
Rat
Rattus norvegicus
Q8CHN6
568
63740
P104
K
D
L
V
K
N
M
P
F
L
K
L
D
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508856
560
61966
V104
L
K
A
G
K
G
Y
V
K
V
L
P
P
T
G
Chicken
Gallus gallus
NP_001007947
561
62425
I105
L
K
D
E
K
D
Y
I
K
V
L
P
E
Q
G
Frog
Xenopus laevis
NP_001091225
453
50814
T16
V
Y
K
E
I
G
L
T
Y
A
F
Q
L
R
N
Zebra Danio
Brachydanio rerio
NP_001082938
572
63710
G104
S
L
C
T
L
K
E
G
M
S
Y
T
K
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7Y2
545
60287
T102
A
H
L
T
Y
S
E
T
L
P
E
K
G
L
S
Honey Bee
Apis mellifera
XP_623988
549
61593
L104
V
K
L
P
E
K
G
L
K
P
K
E
V
L
E
Nematode Worm
Caenorhab. elegans
Q9Y194
552
61079
D102
S
I
H
K
D
D
K
D
K
Q
F
I
S
T
L
Sea Urchin
Strong. purpuratus
XP_790556
422
46078
Poplar Tree
Populus trichocarpa
XP_002304674
540
58782
P103
D
G
W
R
S
E
L
P
K
E
G
L
G
A
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C509
544
59459
P107
K
N
K
T
E
V
L
P
V
K
G
L
G
V
E
Baker's Yeast
Sacchar. cerevisiae
Q05567
589
65547
S128
I
E
D
E
L
I
R
S
D
S
Q
L
M
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
89.2
93.3
N.A.
84.6
85.5
N.A.
77.2
68.4
51.4
63.4
N.A.
46.4
48.2
41
44.3
Protein Similarity:
100
99.8
89.5
96.6
N.A.
92
91.7
N.A.
85.9
81.3
63.3
79.7
N.A.
64.7
66.5
58.7
57.9
P-Site Identity:
100
100
100
100
N.A.
66.6
60
N.A.
6.6
6.6
0
0
N.A.
0
13.3
0
0
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
13.3
33.3
26.6
6.6
N.A.
33.3
26.6
13.3
0
Percent
Protein Identity:
41.9
N.A.
N.A.
40.6
37
N.A.
Protein Similarity:
58.9
N.A.
N.A.
59.1
57
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
6
0
0
0
0
0
0
6
0
0
0
6
6
% A
% Cys:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
30
36
12
0
6
12
0
6
6
0
0
0
36
0
12
% D
% Glu:
0
6
0
18
12
6
12
0
0
6
6
6
6
0
36
% E
% Phe:
0
0
0
0
0
0
0
0
36
0
12
0
0
0
6
% F
% Gly:
0
6
0
6
0
12
6
6
0
0
12
0
18
0
12
% G
% His:
0
6
6
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
6
24
0
6
6
0
6
0
0
0
6
0
0
0
% I
% Lys:
18
18
12
6
48
12
6
0
30
6
42
6
6
36
0
% K
% Leu:
12
6
24
0
12
0
18
6
6
36
12
24
6
18
12
% L
% Met:
0
0
0
0
0
0
36
0
6
0
0
0
6
0
0
% M
% Asn:
0
6
0
0
0
36
0
0
0
0
0
0
0
6
6
% N
% Pro:
0
0
0
6
0
0
0
24
0
12
0
12
6
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
6
6
6
0
6
0
% Q
% Arg:
0
0
0
6
0
0
6
0
0
0
0
0
0
6
0
% R
% Ser:
12
0
0
24
6
6
0
30
0
12
0
0
6
0
6
% S
% Thr:
0
0
0
18
0
0
0
12
0
0
0
6
0
12
0
% T
% Val:
12
0
0
12
0
6
0
6
6
12
0
30
6
6
0
% V
% Trp:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
0
6
0
12
0
6
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _