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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPL1
All Species:
24.85
Human Site:
S135
Identified Species:
34.17
UniProt:
O95470
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95470
NP_003892.2
568
63524
S135
E
K
L
K
E
Y
S
S
M
D
A
F
W
Q
E
Chimpanzee
Pan troglodytes
XP_521504
568
63517
S135
E
K
L
K
E
Y
S
S
M
D
A
F
W
Q
E
Rhesus Macaque
Macaca mulatta
XP_001106861
633
70448
S200
E
K
L
K
E
Y
S
S
M
D
A
F
W
Q
E
Dog
Lupus familis
XP_546150
568
63418
S135
E
K
L
K
E
Y
S
S
M
D
I
F
W
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0X7
568
63659
S135
E
R
L
K
E
Y
S
S
M
D
G
S
W
Q
E
Rat
Rattus norvegicus
Q8CHN6
568
63740
S135
E
R
L
K
E
Y
S
S
M
D
V
F
W
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508856
560
61966
G135
G
D
V
R
W
Q
D
G
R
A
S
G
A
V
Y
Chicken
Gallus gallus
NP_001007947
561
62425
G136
G
D
V
R
W
E
D
G
K
V
S
G
T
V
Y
Frog
Xenopus laevis
NP_001091225
453
50814
Y47
C
K
D
T
E
P
W
Y
L
I
V
L
T
S
G
Zebra Danio
Brachydanio rerio
NP_001082938
572
63710
N135
Y
E
T
L
S
E
V
N
W
A
K
G
K
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7Y2
545
60287
V133
Y
N
W
R
D
G
R
V
S
G
A
V
Y
G
Y
Honey Bee
Apis mellifera
XP_623988
549
61593
R135
K
V
S
G
A
I
Y
R
V
D
I
N
L
L
Q
Nematode Worm
Caenorhab. elegans
Q9Y194
552
61079
N133
Y
E
D
Y
N
T
F
N
I
D
G
G
R
V
S
Sea Urchin
Strong. purpuratus
XP_790556
422
46078
T19
S
G
C
V
Y
A
G
T
D
E
L
A
A
L
A
Poplar Tree
Populus trichocarpa
XP_002304674
540
58782
Y134
G
K
C
S
G
T
V
Y
I
G
G
S
E
S
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C509
544
59459
Y138
G
K
C
S
G
T
V
Y
I
G
G
A
E
S
E
Baker's Yeast
Sacchar. cerevisiae
Q05567
589
65547
I159
L
N
K
L
N
D
L
I
P
H
T
Q
W
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
89.2
93.3
N.A.
84.6
85.5
N.A.
77.2
68.4
51.4
63.4
N.A.
46.4
48.2
41
44.3
Protein Similarity:
100
99.8
89.5
96.6
N.A.
92
91.7
N.A.
85.9
81.3
63.3
79.7
N.A.
64.7
66.5
58.7
57.9
P-Site Identity:
100
100
100
93.3
N.A.
80
86.6
N.A.
0
0
13.3
0
N.A.
6.6
6.6
6.6
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
20
20
20
13.3
N.A.
26.6
26.6
26.6
13.3
Percent
Protein Identity:
41.9
N.A.
N.A.
40.6
37
N.A.
Protein Similarity:
58.9
N.A.
N.A.
59.1
57
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
6
6
0
0
0
12
24
12
12
0
6
% A
% Cys:
6
0
18
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
0
6
6
12
0
6
48
0
0
0
0
0
% D
% Glu:
36
12
0
0
42
12
0
0
0
6
0
0
12
0
53
% E
% Phe:
0
0
0
0
0
0
6
0
0
0
0
30
0
0
0
% F
% Gly:
24
6
0
6
12
6
6
12
0
18
24
24
0
6
6
% G
% His:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
6
0
6
18
6
12
0
0
0
0
% I
% Lys:
6
42
6
36
0
0
0
0
6
0
6
0
6
6
0
% K
% Leu:
6
0
36
12
0
0
6
0
6
0
6
6
6
12
0
% L
% Met:
0
0
0
0
0
0
0
0
36
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
12
0
0
12
0
0
0
6
0
0
0
% N
% Pro:
0
0
0
0
0
6
0
0
6
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
6
0
0
0
0
0
6
0
36
6
% Q
% Arg:
0
12
0
18
0
0
6
6
6
0
0
0
6
0
0
% R
% Ser:
6
0
6
12
6
0
36
36
6
0
12
12
0
18
12
% S
% Thr:
0
0
6
6
0
18
0
6
0
0
6
0
12
0
0
% T
% Val:
0
6
12
6
0
0
18
6
6
6
12
6
0
24
0
% V
% Trp:
0
0
6
0
12
0
6
0
6
0
0
0
42
0
0
% W
% Tyr:
18
0
0
6
6
36
6
18
0
0
0
0
6
0
18
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _