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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPL1
All Species:
18.48
Human Site:
S151
Identified Species:
25.42
UniProt:
O95470
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95470
NP_003892.2
568
63524
S151
R
A
S
G
T
V
Y
S
G
E
E
K
L
T
E
Chimpanzee
Pan troglodytes
XP_521504
568
63517
S151
R
A
S
G
T
V
Y
S
G
E
E
K
L
T
E
Rhesus Macaque
Macaca mulatta
XP_001106861
633
70448
S216
R
A
S
G
T
V
Y
S
G
E
E
K
L
T
E
Dog
Lupus familis
XP_546150
568
63418
S151
K
A
S
G
A
V
Y
S
G
A
E
E
L
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0X7
568
63659
N151
K
A
S
G
A
V
Y
N
G
E
P
K
L
T
E
Rat
Rattus norvegicus
Q8CHN6
568
63740
S151
K
A
S
G
A
V
Y
S
G
E
P
K
L
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508856
560
61966
L151
G
E
E
K
L
T
E
L
L
V
Q
V
Y
G
D
Chicken
Gallus gallus
NP_001007947
561
62425
L152
G
E
E
K
L
T
H
L
L
V
K
V
Y
E
E
Frog
Xenopus laevis
NP_001091225
453
50814
Y63
T
L
M
L
I
S
L
Y
G
I
I
F
Q
S
E
Zebra Danio
Brachydanio rerio
NP_001082938
572
63710
K151
A
V
Y
W
G
D
E
K
L
T
D
L
L
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7Y2
545
60287
T149
P
D
L
V
E
L
V
T
E
V
Y
G
K
A
S
Honey Bee
Apis mellifera
XP_623988
549
61593
A151
M
G
D
I
Y
S
I
A
S
Y
T
N
P
L
H
Nematode Worm
Caenorhab. elegans
Q9Y194
552
61079
A149
A
V
Y
T
D
R
H
A
E
H
I
N
L
L
G
Sea Urchin
Strong. purpuratus
XP_790556
422
46078
W35
T
M
Y
E
D
F
A
W
T
N
P
L
H
P
D
Poplar Tree
Populus trichocarpa
XP_002304674
540
58782
A150
H
F
S
L
I
N
E
A
C
S
M
F
A
H
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C509
544
59459
A154
H
F
S
L
I
N
Q
A
C
S
M
F
A
H
T
Baker's Yeast
Sacchar. cerevisiae
Q05567
589
65547
H175
K
V
S
G
A
V
Y
H
G
G
D
D
L
I
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
89.2
93.3
N.A.
84.6
85.5
N.A.
77.2
68.4
51.4
63.4
N.A.
46.4
48.2
41
44.3
Protein Similarity:
100
99.8
89.5
96.6
N.A.
92
91.7
N.A.
85.9
81.3
63.3
79.7
N.A.
64.7
66.5
58.7
57.9
P-Site Identity:
100
100
100
73.3
N.A.
73.3
80
N.A.
0
6.6
13.3
6.6
N.A.
0
0
6.6
0
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
13.3
20
20
20
N.A.
13.3
6.6
20
6.6
Percent
Protein Identity:
41.9
N.A.
N.A.
40.6
37
N.A.
Protein Similarity:
58.9
N.A.
N.A.
59.1
57
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
40
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
36
0
0
24
0
6
24
0
6
0
0
12
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
6
6
0
12
6
0
0
0
0
12
6
0
0
12
% D
% Glu:
0
12
12
6
6
0
18
0
12
30
24
6
0
6
48
% E
% Phe:
0
12
0
0
0
6
0
0
0
0
0
18
0
0
0
% F
% Gly:
12
6
0
42
6
0
0
0
48
6
0
6
0
6
6
% G
% His:
12
0
0
0
0
0
12
6
0
6
0
0
6
12
12
% H
% Ile:
0
0
0
6
18
0
6
0
0
6
12
0
0
6
0
% I
% Lys:
24
0
0
12
0
0
0
6
0
0
6
30
6
0
6
% K
% Leu:
0
6
6
18
12
6
6
12
18
0
0
12
53
12
0
% L
% Met:
6
6
6
0
0
0
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
6
0
6
0
12
0
0
0
% N
% Pro:
6
0
0
0
0
0
0
0
0
0
18
0
6
6
0
% P
% Gln:
0
0
0
0
0
0
6
0
0
0
6
0
6
0
0
% Q
% Arg:
18
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
53
0
0
12
0
30
6
12
0
0
0
6
6
% S
% Thr:
12
0
0
6
18
12
0
6
6
6
6
0
0
36
12
% T
% Val:
0
18
0
6
0
42
6
0
0
18
0
12
0
6
0
% V
% Trp:
0
0
0
6
0
0
0
6
0
0
0
0
0
0
0
% W
% Tyr:
0
0
18
0
6
0
42
6
0
6
6
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _