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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPL1
All Species:
39.09
Human Site:
S455
Identified Species:
53.75
UniProt:
O95470
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95470
NP_003892.2
568
63524
S455
L
S
V
I
A
L
G
S
R
D
F
D
I
Y
R
Chimpanzee
Pan troglodytes
XP_521504
568
63517
S455
L
S
V
I
A
L
G
S
R
D
F
D
I
Y
R
Rhesus Macaque
Macaca mulatta
XP_001106861
633
70448
S520
L
S
V
I
A
L
G
S
R
D
F
D
I
Y
R
Dog
Lupus familis
XP_546150
568
63418
S455
L
S
V
I
A
L
G
S
R
D
F
D
I
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0X7
568
63659
S455
L
S
V
I
A
L
G
S
N
D
F
D
I
Y
R
Rat
Rattus norvegicus
Q8CHN6
568
63740
S455
L
S
V
I
A
L
G
S
N
D
F
D
I
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508856
560
61966
S447
V
S
V
I
A
L
G
S
R
D
F
D
I
F
R
Chicken
Gallus gallus
NP_001007947
561
62425
S448
V
S
V
L
S
I
G
S
D
T
F
D
I
Y
R
Frog
Xenopus laevis
NP_001091225
453
50814
P343
K
A
G
F
P
L
K
P
F
D
F
R
V
K
G
Zebra Danio
Brachydanio rerio
NP_001082938
572
63710
S451
V
S
V
V
A
L
G
S
D
D
F
D
I
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7Y2
545
60287
T437
F
I
F
G
K
P
A
T
S
V
I
A
L
G
S
Honey Bee
Apis mellifera
XP_623988
549
61593
S440
T
S
V
I
A
L
G
S
N
D
F
H
I
Y
K
Nematode Worm
Caenorhab. elegans
Q9Y194
552
61079
V442
K
P
Y
G
K
S
D
V
S
L
V
A
F
S
G
Sea Urchin
Strong. purpuratus
XP_790556
422
46078
V314
F
V
Y
G
N
P
E
V
S
V
V
G
V
G
S
Poplar Tree
Populus trichocarpa
XP_002304674
540
58782
L432
G
I
K
E
I
P
E
L
F
I
I
G
R
P
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C509
544
59459
L436
G
V
R
E
I
H
E
L
F
V
I
G
K
P
D
Baker's Yeast
Sacchar. cerevisiae
Q05567
589
65547
F481
P
R
Y
S
V
I
S
F
S
S
K
T
L
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
89.2
93.3
N.A.
84.6
85.5
N.A.
77.2
68.4
51.4
63.4
N.A.
46.4
48.2
41
44.3
Protein Similarity:
100
99.8
89.5
96.6
N.A.
92
91.7
N.A.
85.9
81.3
63.3
79.7
N.A.
64.7
66.5
58.7
57.9
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
60
20
73.3
N.A.
0
73.3
0
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
86.6
33.3
93.3
N.A.
13.3
80
0
6.6
Percent
Protein Identity:
41.9
N.A.
N.A.
40.6
37
N.A.
Protein Similarity:
58.9
N.A.
N.A.
59.1
57
N.A.
P-Site Identity:
0
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
0
N.A.
N.A.
0
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
53
0
6
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
6
0
12
59
0
53
0
0
12
% D
% Glu:
0
0
0
12
0
0
18
0
0
0
0
0
0
0
0
% E
% Phe:
12
0
6
6
0
0
0
6
18
0
65
0
6
12
0
% F
% Gly:
12
0
6
18
0
0
59
0
0
0
0
18
0
12
12
% G
% His:
0
0
0
0
0
6
0
0
0
0
0
6
0
0
0
% H
% Ile:
0
12
0
48
12
12
0
0
0
6
18
0
59
0
6
% I
% Lys:
12
0
6
0
12
0
6
0
0
0
6
0
6
6
6
% K
% Leu:
36
0
0
6
0
59
0
12
0
6
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
6
0
0
0
18
0
0
0
0
6
0
% N
% Pro:
6
6
0
0
6
18
0
6
0
0
0
0
0
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
6
6
0
0
0
0
0
30
0
0
6
6
0
53
% R
% Ser:
0
59
0
6
6
6
6
59
24
6
0
0
0
6
12
% S
% Thr:
6
0
0
0
0
0
0
6
0
6
0
6
0
0
0
% T
% Val:
18
12
59
6
6
0
0
12
0
18
12
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
18
0
0
0
0
0
0
0
0
0
0
48
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _