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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPL1
All Species:
22.73
Human Site:
S65
Identified Species:
31.25
UniProt:
O95470
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95470
NP_003892.2
568
63524
S65
E
F
V
F
Q
P
E
S
L
W
S
R
F
K
K
Chimpanzee
Pan troglodytes
XP_521504
568
63517
S65
E
F
V
F
Q
P
E
S
L
W
S
R
F
K
K
Rhesus Macaque
Macaca mulatta
XP_001106861
633
70448
S130
E
F
V
F
Q
P
E
S
L
W
S
R
F
K
K
Dog
Lupus familis
XP_546150
568
63418
S65
D
F
V
F
Q
P
E
S
L
W
S
R
F
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0X7
568
63659
S65
E
L
I
F
Q
P
E
S
L
W
S
R
F
K
K
Rat
Rattus norvegicus
Q8CHN6
568
63740
S65
E
L
I
F
Q
P
E
S
L
W
S
R
F
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508856
560
61966
R67
R
G
R
K
K
F
F
R
V
L
R
K
L
P
I
Chicken
Gallus gallus
NP_001007947
561
62425
R68
R
T
K
K
Q
F
F
R
L
L
R
K
M
P
F
Frog
Xenopus laevis
NP_001091225
453
50814
Zebra Danio
Brachydanio rerio
NP_001082938
572
63710
K67
S
L
T
S
R
V
K
K
Q
F
F
R
I
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7Y2
545
60287
A65
K
R
Q
F
F
K
F
A
K
K
I
P
A
V
R
Honey Bee
Apis mellifera
XP_623988
549
61593
A66
N
L
M
H
F
I
P
A
I
R
N
K
I
D
Q
Nematode Worm
Caenorhab. elegans
Q9Y194
552
61079
A65
P
I
L
K
R
M
G
A
Y
V
F
S
L
L
R
Sea Urchin
Strong. purpuratus
XP_790556
422
46078
Poplar Tree
Populus trichocarpa
XP_002304674
540
58782
S65
I
L
G
F
L
I
T
S
I
K
M
V
P
G
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C509
544
59459
L69
L
I
G
F
I
M
G
L
L
K
M
I
P
G
V
Baker's Yeast
Sacchar. cerevisiae
Q05567
589
65547
G80
F
Y
L
L
K
V
Y
G
P
V
R
L
A
V
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
89.2
93.3
N.A.
84.6
85.5
N.A.
77.2
68.4
51.4
63.4
N.A.
46.4
48.2
41
44.3
Protein Similarity:
100
99.8
89.5
96.6
N.A.
92
91.7
N.A.
85.9
81.3
63.3
79.7
N.A.
64.7
66.5
58.7
57.9
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
0
13.3
0
6.6
N.A.
6.6
0
0
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
20
20
0
33.3
N.A.
26.6
40
26.6
0
Percent
Protein Identity:
41.9
N.A.
N.A.
40.6
37
N.A.
Protein Similarity:
58.9
N.A.
N.A.
59.1
57
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
18
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% D
% Glu:
30
0
0
0
0
0
36
0
0
0
0
0
0
0
0
% E
% Phe:
6
24
0
53
12
12
18
0
0
6
12
0
36
0
6
% F
% Gly:
0
6
12
0
0
0
12
6
0
0
0
0
0
12
0
% G
% His:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
12
12
0
6
12
0
0
12
0
6
6
12
6
6
% I
% Lys:
6
0
6
18
12
6
6
6
6
18
0
18
0
36
30
% K
% Leu:
6
30
12
6
6
0
0
6
48
12
0
6
12
6
0
% L
% Met:
0
0
6
0
0
12
0
0
0
0
12
0
6
0
0
% M
% Asn:
6
0
0
0
0
0
0
0
0
0
6
0
0
0
6
% N
% Pro:
6
0
0
0
0
36
6
0
6
0
0
6
12
12
0
% P
% Gln:
0
0
6
0
42
0
0
0
6
0
0
0
0
0
6
% Q
% Arg:
12
6
6
0
12
0
0
12
0
6
18
42
0
0
24
% R
% Ser:
6
0
0
6
0
0
0
42
0
0
36
6
0
0
0
% S
% Thr:
0
6
6
0
0
0
6
0
0
0
0
0
0
0
0
% T
% Val:
0
0
24
0
0
12
0
0
6
12
0
6
0
12
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
36
0
0
0
0
0
% W
% Tyr:
0
6
0
0
0
0
6
0
6
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _