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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPL1
All Species:
21.82
Human Site:
T232
Identified Species:
30
UniProt:
O95470
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95470
NP_003892.2
568
63524
T232
A
F
E
K
G
I
K
T
P
E
I
V
A
P
Q
Chimpanzee
Pan troglodytes
XP_521504
568
63517
T232
A
F
E
K
G
I
K
T
P
E
I
V
A
P
Q
Rhesus Macaque
Macaca mulatta
XP_001106861
633
70448
T297
A
F
E
K
G
I
K
T
P
E
I
V
A
P
Q
Dog
Lupus familis
XP_546150
568
63418
T232
A
F
E
N
G
I
K
T
P
E
I
V
A
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0X7
568
63659
T232
A
L
E
K
G
I
K
T
P
E
I
V
A
P
E
Rat
Rattus norvegicus
Q8CHN6
568
63740
T232
A
L
E
K
G
I
K
T
P
E
I
V
A
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508856
560
61966
H224
A
Y
E
K
G
I
K
H
P
E
I
V
A
P
V
Chicken
Gallus gallus
NP_001007947
561
62425
H225
A
Y
E
R
G
I
K
H
P
E
M
L
V
P
V
Frog
Xenopus laevis
NP_001091225
453
50814
L135
Q
E
Q
V
M
E
K
L
K
K
E
Y
S
S
I
Zebra Danio
Brachydanio rerio
NP_001082938
572
63710
H228
A
H
E
R
G
I
K
H
P
E
I
I
A
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7Y2
545
60287
P222
E
Y
K
G
I
T
R
P
N
I
V
V
P
K
T
Honey Bee
Apis mellifera
XP_623988
549
61593
P223
K
N
P
E
I
I
M
P
V
T
A
H
S
A
F
Nematode Worm
Caenorhab. elegans
Q9Y194
552
61079
H227
A
H
S
L
G
I
E
H
P
V
I
L
A
C
K
Sea Urchin
Strong. purpuratus
XP_790556
422
46078
A107
E
I
I
A
P
V
S
A
H
A
A
F
D
K
A
Poplar Tree
Populus trichocarpa
XP_002304674
540
58782
R225
K
A
K
K
G
I
K
R
P
E
M
I
I
P
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C509
544
59459
R229
K
Y
K
K
G
I
T
R
P
E
M
I
I
P
E
Baker's Yeast
Sacchar. cerevisiae
Q05567
589
65547
E258
L
H
H
R
G
I
T
E
P
E
I
I
A
P
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
89.2
93.3
N.A.
84.6
85.5
N.A.
77.2
68.4
51.4
63.4
N.A.
46.4
48.2
41
44.3
Protein Similarity:
100
99.8
89.5
96.6
N.A.
92
91.7
N.A.
85.9
81.3
63.3
79.7
N.A.
64.7
66.5
58.7
57.9
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
80
53.3
6.6
66.6
N.A.
6.6
6.6
40
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
80
26.6
80
N.A.
33.3
20
60
6.6
Percent
Protein Identity:
41.9
N.A.
N.A.
40.6
37
N.A.
Protein Similarity:
58.9
N.A.
N.A.
59.1
57
N.A.
P-Site Identity:
46.6
N.A.
N.A.
40
46.6
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
73.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
59
6
0
6
0
0
0
6
0
6
12
0
59
6
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% D
% Glu:
12
6
53
6
0
6
6
6
0
71
6
0
0
0
24
% E
% Phe:
0
24
0
0
0
0
0
0
0
0
0
6
0
0
6
% F
% Gly:
0
0
0
6
77
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
18
6
0
0
0
0
24
6
0
0
6
0
0
0
% H
% Ile:
0
6
6
0
12
83
0
0
0
6
59
24
12
0
12
% I
% Lys:
18
0
18
48
0
0
65
0
6
6
0
0
0
12
6
% K
% Leu:
6
12
0
6
0
0
0
6
0
0
0
12
0
0
0
% L
% Met:
0
0
0
0
6
0
6
0
0
0
18
0
0
0
0
% M
% Asn:
0
6
0
6
0
0
0
0
6
0
0
0
0
0
0
% N
% Pro:
0
0
6
0
6
0
0
12
77
0
0
0
6
71
0
% P
% Gln:
6
0
6
0
0
0
0
0
0
0
0
0
0
0
24
% Q
% Arg:
0
0
0
18
0
0
6
12
0
0
0
0
0
0
0
% R
% Ser:
0
0
6
0
0
0
6
0
0
0
0
0
12
6
0
% S
% Thr:
0
0
0
0
0
6
12
36
0
6
0
0
0
0
6
% T
% Val:
0
0
0
6
0
6
0
0
6
6
6
48
6
0
18
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
24
0
0
0
0
0
0
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _