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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPL1
All Species:
29.7
Human Site:
T552
Identified Species:
40.83
UniProt:
O95470
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95470
NP_003892.2
568
63524
T552
F
L
D
S
L
Y
S
T
D
T
V
T
Q
G
S
Chimpanzee
Pan troglodytes
XP_521504
568
63517
T552
F
L
D
S
L
Y
S
T
D
T
V
I
Q
G
S
Rhesus Macaque
Macaca mulatta
XP_001106861
633
70448
T617
F
L
D
S
L
Y
S
T
D
T
V
T
Q
G
S
Dog
Lupus familis
XP_546150
568
63418
T552
F
L
D
S
L
F
S
T
D
T
V
T
P
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0X7
568
63659
T552
F
L
D
C
L
Y
T
T
D
P
V
T
Q
G
N
Rat
Rattus norvegicus
Q8CHN6
568
63740
T552
F
L
D
S
L
Y
S
T
D
P
V
T
Q
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508856
560
61966
T544
F
L
D
S
L
Y
S
T
E
N
S
S
R
G
G
Chicken
Gallus gallus
NP_001007947
561
62425
T545
Y
L
D
G
L
Y
S
T
D
V
P
G
S
E
K
Frog
Xenopus laevis
NP_001091225
453
50814
H437
N
H
Q
S
S
T
V
H
R
N
R
V
A
E
N
Zebra Danio
Brachydanio rerio
NP_001082938
572
63710
T548
F
L
D
C
L
Y
S
T
E
V
P
K
M
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7Y2
545
60287
V530
D
R
S
V
I
G
E
V
T
R
L
F
L
H
S
Honey Bee
Apis mellifera
XP_623988
549
61593
M534
A
K
C
F
L
D
S
M
Y
F
T
P
E
N
E
Nematode Worm
Caenorhab. elegans
Q9Y194
552
61079
V535
P
K
S
V
V
D
E
V
I
A
L
Y
I
D
A
Sea Urchin
Strong. purpuratus
XP_790556
422
46078
M407
D
R
S
L
V
T
D
M
A
R
G
Y
L
D
A
Poplar Tree
Populus trichocarpa
XP_002304674
540
58782
R525
A
A
G
K
I
P
D
R
G
M
V
Q
E
L
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C509
544
59459
R529
A
A
G
K
M
P
D
R
G
M
V
N
E
L
L
Baker's Yeast
Sacchar. cerevisiae
Q05567
589
65547
L574
D
K
L
I
V
G
F
L
D
A
L
Y
K
L
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
89.2
93.3
N.A.
84.6
85.5
N.A.
77.2
68.4
51.4
63.4
N.A.
46.4
48.2
41
44.3
Protein Similarity:
100
99.8
89.5
96.6
N.A.
92
91.7
N.A.
85.9
81.3
63.3
79.7
N.A.
64.7
66.5
58.7
57.9
P-Site Identity:
100
93.3
100
80
N.A.
73.3
86.6
N.A.
60
46.6
6.6
46.6
N.A.
6.6
13.3
0
0
P-Site Similarity:
100
93.3
100
86.6
N.A.
86.6
93.3
N.A.
80
53.3
13.3
60
N.A.
20
20
20
13.3
Percent
Protein Identity:
41.9
N.A.
N.A.
40.6
37
N.A.
Protein Similarity:
58.9
N.A.
N.A.
59.1
57
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
12
0
0
0
0
0
0
6
12
0
0
6
0
12
% A
% Cys:
0
0
6
12
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
18
0
53
0
0
12
18
0
48
0
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
0
12
0
12
0
0
0
18
12
6
% E
% Phe:
48
0
0
6
0
6
6
0
0
6
0
6
0
0
0
% F
% Gly:
0
0
12
6
0
12
0
0
12
0
6
6
0
36
12
% G
% His:
0
6
0
0
0
0
0
6
0
0
0
0
0
6
0
% H
% Ile:
0
0
0
6
12
0
0
0
6
0
0
6
6
0
0
% I
% Lys:
0
18
0
12
0
0
0
0
0
0
0
6
6
0
6
% K
% Leu:
0
53
6
6
59
0
0
6
0
0
18
0
12
18
12
% L
% Met:
0
0
0
0
6
0
0
12
0
12
0
0
6
0
0
% M
% Asn:
6
0
0
0
0
0
0
0
0
12
0
6
0
6
24
% N
% Pro:
6
0
0
0
0
12
0
0
0
12
12
6
6
0
0
% P
% Gln:
0
0
6
0
0
0
0
0
0
0
0
6
30
6
0
% Q
% Arg:
0
12
0
0
0
0
0
12
6
12
6
0
6
0
0
% R
% Ser:
0
0
18
42
6
0
53
0
0
0
6
6
6
6
30
% S
% Thr:
0
0
0
0
0
12
6
53
6
24
6
30
0
0
0
% T
% Val:
0
0
0
12
18
0
6
12
0
12
48
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
48
0
0
6
0
0
18
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _