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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPL1
All Species:
27.88
Human Site:
Y331
Identified Species:
38.33
UniProt:
O95470
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95470
NP_003892.2
568
63524
Y331
V
F
M
E
K
A
G
Y
P
L
E
H
P
F
D
Chimpanzee
Pan troglodytes
XP_521504
568
63517
Y331
V
F
M
E
K
A
G
Y
P
L
E
H
P
F
D
Rhesus Macaque
Macaca mulatta
XP_001106861
633
70448
Y396
V
F
M
E
K
A
G
Y
P
L
E
H
P
F
D
Dog
Lupus familis
XP_546150
568
63418
Y331
V
F
M
E
K
A
G
Y
P
L
E
Q
P
F
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0X7
568
63659
Y331
V
F
M
E
K
A
G
Y
P
L
E
K
P
F
D
Rat
Rattus norvegicus
Q8CHN6
568
63740
Y331
V
F
M
E
K
A
G
Y
P
L
E
K
P
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508856
560
61966
Y323
T
F
M
E
K
A
G
Y
P
L
E
Q
Q
F
D
Chicken
Gallus gallus
NP_001007947
561
62425
F324
V
F
M
E
K
A
G
F
P
L
K
R
L
F
D
Frog
Xenopus laevis
NP_001091225
453
50814
I221
T
S
G
G
T
E
S
I
L
M
A
C
K
A
Y
Zebra Danio
Brachydanio rerio
NP_001082938
572
63710
G327
I
V
F
M
E
K
A
G
F
K
L
A
P
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7Y2
545
60287
A314
C
L
G
S
F
V
V
A
L
V
R
N
A
G
Y
Honey Bee
Apis mellifera
XP_623988
549
61593
G316
I
C
F
M
K
N
A
G
F
D
I
S
P
F
D
Nematode Worm
Caenorhab. elegans
Q9Y194
552
61079
F320
L
G
G
F
M
I
P
F
M
N
D
A
G
Y
L
Sea Urchin
Strong. purpuratus
XP_790556
422
46078
F192
L
G
G
F
L
V
P
F
M
E
K
A
G
F
P
Poplar Tree
Populus trichocarpa
XP_002304674
540
58782
C310
I
C
F
H
V
D
L
C
L
G
G
F
V
L
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C509
544
59459
C314
I
C
F
H
V
D
L
C
L
G
G
F
V
L
P
Baker's Yeast
Sacchar. cerevisiae
Q05567
589
65547
Y358
S
F
M
E
K
A
G
Y
K
N
L
P
L
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
89.2
93.3
N.A.
84.6
85.5
N.A.
77.2
68.4
51.4
63.4
N.A.
46.4
48.2
41
44.3
Protein Similarity:
100
99.8
89.5
96.6
N.A.
92
91.7
N.A.
85.9
81.3
63.3
79.7
N.A.
64.7
66.5
58.7
57.9
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
80
73.3
0
20
N.A.
0
26.6
0
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
80
86.6
6.6
33.3
N.A.
13.3
33.3
26.6
26.6
Percent
Protein Identity:
41.9
N.A.
N.A.
40.6
37
N.A.
Protein Similarity:
58.9
N.A.
N.A.
59.1
57
N.A.
P-Site Identity:
0
N.A.
N.A.
0
53.3
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
6.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
53
12
6
0
0
6
18
6
6
0
% A
% Cys:
6
18
0
0
0
0
0
12
0
0
0
6
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
0
0
6
6
0
0
0
65
% D
% Glu:
0
0
0
53
6
6
0
0
0
6
42
0
0
0
0
% E
% Phe:
0
53
24
12
6
0
0
18
12
0
0
12
0
65
0
% F
% Gly:
0
12
24
6
0
0
53
12
0
12
12
0
12
6
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
18
0
0
0
% H
% Ile:
24
0
0
0
0
6
0
6
0
0
6
0
0
0
0
% I
% Lys:
0
0
0
0
59
6
0
0
6
6
12
12
6
0
0
% K
% Leu:
12
6
0
0
6
0
12
0
24
48
12
0
12
18
6
% L
% Met:
0
0
53
12
6
0
0
0
12
6
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
6
0
0
0
12
0
6
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
48
0
0
6
48
0
18
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
12
6
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
6
6
0
0
0
% R
% Ser:
6
6
0
6
0
0
6
0
0
0
0
6
0
0
0
% S
% Thr:
12
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% T
% Val:
42
6
0
0
12
12
6
0
0
6
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
48
0
0
0
0
0
6
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _