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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPL1
All Species:
45.76
Human Site:
Y366
Identified Species:
62.92
UniProt:
O95470
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95470
NP_003892.2
568
63524
Y366
K
G
S
S
L
V
L
Y
S
D
K
K
Y
R
N
Chimpanzee
Pan troglodytes
XP_521504
568
63517
Y366
K
G
S
S
L
V
L
Y
S
D
K
K
Y
R
N
Rhesus Macaque
Macaca mulatta
XP_001106861
633
70448
Y431
K
G
S
S
L
V
L
Y
S
D
K
K
Y
R
N
Dog
Lupus familis
XP_546150
568
63418
Y366
K
G
S
S
V
L
L
Y
S
D
K
K
Y
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0X7
568
63659
Y366
K
G
S
S
V
V
M
Y
S
N
E
K
Y
R
T
Rat
Rattus norvegicus
Q8CHN6
568
63740
Y366
K
G
S
S
V
V
M
Y
S
N
E
K
Y
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508856
560
61966
Y358
K
G
S
S
V
V
L
Y
S
D
K
K
Y
R
H
Chicken
Gallus gallus
NP_001007947
561
62425
Y359
K
G
S
S
V
V
L
Y
S
D
K
K
Y
R
S
Frog
Xenopus laevis
NP_001091225
453
50814
A256
H
A
A
F
D
K
A
A
H
Y
F
G
M
K
I
Zebra Danio
Brachydanio rerio
NP_001082938
572
63710
Y362
K
G
S
S
V
V
L
Y
S
N
R
K
F
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7Y2
545
60287
G349
K
Y
G
F
A
P
K
G
S
S
V
I
L
Y
S
Honey Bee
Apis mellifera
XP_623988
549
61593
Y351
K
G
S
S
L
I
L
Y
R
N
K
K
I
R
H
Nematode Worm
Caenorhab. elegans
Q9Y194
552
61079
S355
Y
G
C
T
P
K
G
S
S
I
V
M
Y
R
S
Sea Urchin
Strong. purpuratus
XP_790556
422
46078
S227
Y
G
Y
A
P
K
G
S
S
V
I
M
Y
S
E
Poplar Tree
Populus trichocarpa
XP_002304674
540
58782
K345
S
I
S
A
D
V
H
K
Y
G
L
A
P
K
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C509
544
59459
K349
S
I
S
V
D
V
H
K
Y
G
L
A
P
K
G
Baker's Yeast
Sacchar. cerevisiae
Q05567
589
65547
Y393
K
G
S
S
V
I
M
Y
R
N
S
D
L
R
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
89.2
93.3
N.A.
84.6
85.5
N.A.
77.2
68.4
51.4
63.4
N.A.
46.4
48.2
41
44.3
Protein Similarity:
100
99.8
89.5
96.6
N.A.
92
91.7
N.A.
85.9
81.3
63.3
79.7
N.A.
64.7
66.5
58.7
57.9
P-Site Identity:
100
100
100
80
N.A.
66.6
66.6
N.A.
86.6
86.6
0
66.6
N.A.
13.3
66.6
26.6
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
100
13.3
100
N.A.
20
86.6
40
26.6
Percent
Protein Identity:
41.9
N.A.
N.A.
40.6
37
N.A.
Protein Similarity:
58.9
N.A.
N.A.
59.1
57
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
40
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
20
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
12
6
0
6
6
0
0
0
12
0
0
0
% A
% Cys:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
18
0
0
0
0
36
0
6
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
6
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
6
0
6
0
0
% F
% Gly:
0
77
6
0
0
0
12
6
0
12
0
6
0
0
12
% G
% His:
6
0
0
0
0
0
12
0
6
0
0
0
0
0
18
% H
% Ile:
0
12
0
0
0
12
0
0
0
6
6
6
6
0
6
% I
% Lys:
71
0
0
0
0
18
6
12
0
0
42
59
0
18
6
% K
% Leu:
0
0
0
0
24
6
48
0
0
0
12
0
12
0
0
% L
% Met:
0
0
0
0
0
0
18
0
0
0
0
12
6
0
6
% M
% Asn:
0
0
0
0
0
0
0
0
0
30
0
0
0
0
18
% N
% Pro:
0
0
0
0
12
6
0
0
0
0
0
0
12
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
12
0
6
0
0
71
0
% R
% Ser:
12
0
77
65
0
0
0
12
71
6
6
0
0
6
24
% S
% Thr:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
6
% T
% Val:
0
0
0
6
42
59
0
0
0
6
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
6
6
0
0
0
0
65
12
6
0
0
59
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _