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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPL1
All Species:
33.94
Human Site:
Y371
Identified Species:
46.67
UniProt:
O95470
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95470
NP_003892.2
568
63524
Y371
V
L
Y
S
D
K
K
Y
R
N
Y
Q
F
F
V
Chimpanzee
Pan troglodytes
XP_521504
568
63517
Y371
V
L
Y
S
D
K
K
Y
R
N
Y
Q
F
F
V
Rhesus Macaque
Macaca mulatta
XP_001106861
633
70448
Y436
V
L
Y
S
D
K
K
Y
R
N
Y
Q
F
F
V
Dog
Lupus familis
XP_546150
568
63418
Y371
L
L
Y
S
D
K
K
Y
R
S
H
Q
F
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0X7
568
63659
Y371
V
M
Y
S
N
E
K
Y
R
T
Y
Q
F
F
V
Rat
Rattus norvegicus
Q8CHN6
568
63740
Y371
V
M
Y
S
N
E
K
Y
R
K
Y
Q
F
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508856
560
61966
Y363
V
L
Y
S
D
K
K
Y
R
H
Y
Q
F
F
V
Chicken
Gallus gallus
NP_001007947
561
62425
Y364
V
L
Y
S
D
K
K
Y
R
S
Y
Q
Y
F
V
Frog
Xenopus laevis
NP_001091225
453
50814
M261
K
A
A
H
Y
F
G
M
K
I
V
H
I
P
V
Zebra Danio
Brachydanio rerio
NP_001082938
572
63710
F367
V
L
Y
S
N
R
K
F
R
H
Y
Q
Y
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7Y2
545
60287
L354
P
K
G
S
S
V
I
L
Y
S
D
K
K
Y
K
Honey Bee
Apis mellifera
XP_623988
549
61593
I356
I
L
Y
R
N
K
K
I
R
H
Y
Q
Y
T
I
Nematode Worm
Caenorhab. elegans
Q9Y194
552
61079
Y360
K
G
S
S
I
V
M
Y
R
S
K
E
L
H
H
Sea Urchin
Strong. purpuratus
XP_790556
422
46078
Y232
K
G
S
S
V
I
M
Y
S
E
K
K
F
R
H
Poplar Tree
Populus trichocarpa
XP_002304674
540
58782
P350
V
H
K
Y
G
L
A
P
K
G
T
S
V
V
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C509
544
59459
P354
V
H
K
Y
G
L
A
P
K
G
T
S
T
V
L
Baker's Yeast
Sacchar. cerevisiae
Q05567
589
65547
L398
I
M
Y
R
N
S
D
L
R
M
H
Q
Y
Y
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
89.2
93.3
N.A.
84.6
85.5
N.A.
77.2
68.4
51.4
63.4
N.A.
46.4
48.2
41
44.3
Protein Similarity:
100
99.8
89.5
96.6
N.A.
92
91.7
N.A.
85.9
81.3
63.3
79.7
N.A.
64.7
66.5
58.7
57.9
P-Site Identity:
100
100
100
80
N.A.
73.3
73.3
N.A.
93.3
86.6
6.6
66.6
N.A.
6.6
46.6
20
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
100
13.3
100
N.A.
26.6
80
33.3
26.6
Percent
Protein Identity:
41.9
N.A.
N.A.
40.6
37
N.A.
Protein Similarity:
58.9
N.A.
N.A.
59.1
57
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
26.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
0
0
0
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
36
0
6
0
0
0
6
0
0
0
0
% D
% Glu:
0
0
0
0
0
12
0
0
0
6
0
6
0
0
0
% E
% Phe:
0
0
0
0
0
6
0
6
0
0
0
0
48
53
0
% F
% Gly:
0
12
6
0
12
0
6
0
0
12
0
0
0
0
0
% G
% His:
0
12
0
6
0
0
0
0
0
18
12
6
0
6
12
% H
% Ile:
12
0
0
0
6
6
6
6
0
6
0
0
6
0
6
% I
% Lys:
18
6
12
0
0
42
59
0
18
6
12
12
6
0
6
% K
% Leu:
6
48
0
0
0
12
0
12
0
0
0
0
6
0
12
% L
% Met:
0
18
0
0
0
0
12
6
0
6
0
0
0
0
0
% M
% Asn:
0
0
0
0
30
0
0
0
0
18
0
0
0
0
0
% N
% Pro:
6
0
0
0
0
0
0
12
0
0
0
0
0
6
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
65
0
0
0
% Q
% Arg:
0
0
0
12
0
6
0
0
71
0
0
0
0
6
0
% R
% Ser:
0
0
12
71
6
6
0
0
6
24
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
6
12
0
6
6
0
% T
% Val:
59
0
0
0
6
12
0
0
0
0
6
0
6
12
65
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
65
12
6
0
0
59
6
0
53
0
24
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _