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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGPL1
All Species:
42.12
Human Site:
Y387
Identified Species:
57.92
UniProt:
O95470
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95470
NP_003892.2
568
63524
Y387
T
D
W
Q
G
G
I
Y
A
S
P
T
I
A
G
Chimpanzee
Pan troglodytes
XP_521504
568
63517
Y387
T
D
W
Q
G
G
I
Y
A
S
P
T
I
A
G
Rhesus Macaque
Macaca mulatta
XP_001106861
633
70448
Y452
T
D
W
Q
G
G
I
Y
A
S
P
T
I
A
G
Dog
Lupus familis
XP_546150
568
63418
Y387
T
D
W
Q
G
G
I
Y
A
S
P
T
I
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0X7
568
63659
Y387
A
D
W
Q
G
G
V
Y
A
S
P
S
I
A
G
Rat
Rattus norvegicus
Q8CHN6
568
63740
Y387
A
D
W
Q
G
G
I
Y
A
S
P
S
I
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508856
560
61966
Y379
P
D
W
Q
G
G
I
Y
A
S
P
T
I
A
G
Chicken
Gallus gallus
NP_001007947
561
62425
Y380
P
D
W
Q
G
G
I
Y
A
S
P
S
I
A
G
Frog
Xenopus laevis
NP_001091225
453
50814
V277
K
A
T
M
Q
V
D
V
K
A
M
K
R
A
I
Zebra Danio
Brachydanio rerio
NP_001082938
572
63710
Y383
P
D
W
Q
G
G
I
Y
A
S
P
S
M
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V7Y2
545
60287
D370
H
Q
F
T
V
T
T
D
W
P
G
G
V
Y
G
Honey Bee
Apis mellifera
XP_623988
549
61593
Y372
T
D
W
P
G
G
I
Y
G
S
P
T
V
S
G
Nematode Worm
Caenorhab. elegans
Q9Y194
552
61079
W376
Q
Y
F
S
V
A
D
W
C
G
G
I
Y
A
T
Sea Urchin
Strong. purpuratus
XP_790556
422
46078
W248
Q
F
F
V
S
P
D
W
T
G
G
I
Y
A
T
Poplar Tree
Populus trichocarpa
XP_002304674
540
58782
H366
R
N
H
D
I
R
K
H
Q
F
V
A
V
T
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C509
544
59459
H370
R
N
H
E
I
R
K
H
Q
F
V
A
V
T
E
Baker's Yeast
Sacchar. cerevisiae
Q05567
589
65547
Y414
P
A
W
T
G
G
L
Y
G
S
P
T
L
A
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
89.2
93.3
N.A.
84.6
85.5
N.A.
77.2
68.4
51.4
63.4
N.A.
46.4
48.2
41
44.3
Protein Similarity:
100
99.8
89.5
96.6
N.A.
92
91.7
N.A.
85.9
81.3
63.3
79.7
N.A.
64.7
66.5
58.7
57.9
P-Site Identity:
100
100
100
100
N.A.
80
86.6
N.A.
93.3
86.6
6.6
80
N.A.
6.6
73.3
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
93.3
13.3
93.3
N.A.
20
86.6
20
20
Percent
Protein Identity:
41.9
N.A.
N.A.
40.6
37
N.A.
Protein Similarity:
58.9
N.A.
N.A.
59.1
57
N.A.
P-Site Identity:
0
N.A.
N.A.
0
60
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
0
0
6
0
0
53
6
0
12
0
77
0
% A
% Cys:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% C
% Asp:
0
59
0
6
0
0
18
6
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
12
% E
% Phe:
0
6
18
0
0
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
0
0
0
0
65
65
0
0
12
12
18
6
0
0
71
% G
% His:
6
0
12
0
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
12
0
53
0
0
0
0
12
48
0
6
% I
% Lys:
6
0
0
0
0
0
12
0
6
0
0
6
0
0
0
% K
% Leu:
0
0
0
0
0
0
6
0
0
0
0
0
6
0
0
% L
% Met:
0
0
0
6
0
0
0
0
0
0
6
0
6
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
24
0
0
6
0
6
0
0
0
6
65
0
0
0
0
% P
% Gln:
12
6
0
53
6
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
0
12
0
0
0
0
0
0
6
0
0
% R
% Ser:
0
0
0
6
6
0
0
0
0
65
0
24
0
6
0
% S
% Thr:
30
0
6
12
0
6
6
0
6
0
0
42
0
12
12
% T
% Val:
0
0
0
6
12
6
6
6
0
0
12
0
24
0
0
% V
% Trp:
0
0
65
0
0
0
0
12
6
0
0
0
0
0
0
% W
% Tyr:
0
6
0
0
0
0
0
65
0
0
0
0
12
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _