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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SYNGR4
All Species:
15.76
Human Site:
T221
Identified Species:
38.52
UniProt:
O95473
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95473
NP_036583.2
234
25820
T221
S
A
L
S
P
C
L
T
A
P
K
S
P
R
L
Chimpanzee
Pan troglodytes
XP_001154702
330
35837
T317
S
A
L
S
P
C
L
T
A
P
K
A
P
R
L
Rhesus Macaque
Macaca mulatta
XP_001113574
234
25682
T221
S
A
L
S
P
C
L
T
A
P
K
A
P
R
L
Dog
Lupus familis
XP_854883
225
24613
T212
S
A
S
S
P
Y
L
T
T
P
K
A
P
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1L2
233
25776
T221
A
L
S
P
Y
M
T
T
P
K
A
P
R
L
A
Rat
Rattus norvegicus
Q62876
234
25650
D223
Q
H
P
A
N
A
F
D
A
E
P
Q
G
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512157
220
24248
N207
Q
Q
P
P
F
T
Q
N
V
E
S
T
E
G
Y
Chicken
Gallus gallus
NP_001007835
230
25156
T217
Q
S
P
P
F
T
E
T
S
D
T
N
P
K
G
Frog
Xenopus laevis
NP_001086788
217
24253
S206
Q
S
P
P
F
T
N
S
N
E
T
G
D
Y
Q
Zebra Danio
Brachydanio rerio
NP_001006067
223
24637
D207
E
Y
T
G
Y
N
A
D
M
E
A
N
Y
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.5
91.8
65.8
N.A.
72.6
34.6
N.A.
32.9
32.4
37.6
32
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
67.2
95.7
75.2
N.A.
85.9
51.2
N.A.
47.8
50
54.2
49.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
73.3
N.A.
6.6
6.6
N.A.
0
13.3
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
13.3
13.3
N.A.
6.6
40
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
40
0
10
0
10
10
0
40
0
20
30
0
0
10
% A
% Cys:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
20
0
10
0
0
10
10
0
% D
% Glu:
10
0
0
0
0
0
10
0
0
40
0
0
10
0
0
% E
% Phe:
0
0
0
0
30
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
10
10
10
20
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
40
0
0
10
0
% K
% Leu:
0
10
30
0
0
0
40
0
0
0
0
0
0
10
40
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
10
10
10
10
0
0
20
0
0
0
% N
% Pro:
0
0
40
40
40
0
0
0
10
40
10
10
50
0
0
% P
% Gln:
40
10
0
0
0
0
10
0
0
0
0
10
0
0
20
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
40
0
% R
% Ser:
40
20
20
40
0
0
0
10
10
0
10
10
0
0
0
% S
% Thr:
0
0
10
0
0
30
10
60
10
0
20
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
20
10
0
0
0
0
0
0
10
20
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _