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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIX6
All Species:
17.58
Human Site:
S198
Identified Species:
32.22
UniProt:
O95475
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95475
NP_031400.2
246
27687
S198
R
L
Q
Q
Q
V
L
S
Q
G
S
G
R
A
L
Chimpanzee
Pan troglodytes
XP_522870
514
56142
S466
R
L
Q
Q
Q
V
L
S
Q
G
S
G
R
A
L
Rhesus Macaque
Macaca mulatta
XP_001094228
396
43626
S348
R
L
Q
Q
Q
V
L
S
Q
G
S
G
R
A
L
Dog
Lupus familis
XP_547840
343
38064
S295
R
L
Q
Q
Q
V
L
S
Q
G
S
G
R
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ28
246
27723
S198
R
L
Q
Q
Q
V
L
S
Q
G
P
G
R
V
L
Rat
Rattus norvegicus
NP_076480
337
35742
A289
P
S
G
M
R
S
L
A
E
P
G
C
P
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O93307
246
27619
A198
R
L
Q
Q
Q
V
L
A
Q
G
S
G
R
S
L
Frog
Xenopus laevis
P79937
390
42868
Q332
N
A
R
R
R
I
V
Q
P
M
I
D
Q
S
N
Zebra Danio
Brachydanio rerio
NP_957399
245
27632
L197
N
R
L
Q
Q
Q
V
L
S
G
G
S
V
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95RW8
487
52401
A236
M
G
C
R
S
R
R
A
D
G
A
A
S
P
T
Honey Bee
Apis mellifera
XP_623764
475
51466
E378
H
V
Q
H
Q
L
P
E
R
I
S
D
G
S
R
Nematode Worm
Caenorhab. elegans
Q23175
439
49618
E359
V
E
V
E
A
D
I
E
P
P
K
K
R
S
K
Sea Urchin
Strong. purpuratus
XP_781696
324
36468
A250
N
R
R
Q
R
D
R
A
A
A
A
K
N
R
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
61.3
70.5
N.A.
97.9
59
N.A.
N.A.
93.5
20.2
90.6
N.A.
39.2
41.2
35
57.4
Protein Similarity:
100
47.8
61.3
70.8
N.A.
99.1
65.5
N.A.
N.A.
95.9
33.3
94.3
N.A.
43.7
45.4
42.1
63.5
P-Site Identity:
100
100
100
100
N.A.
86.6
6.6
N.A.
N.A.
86.6
0
20
N.A.
6.6
20
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
26.6
N.A.
N.A.
100
46.6
26.6
N.A.
26.6
46.6
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
31
8
8
16
8
0
31
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
16
0
0
8
0
0
16
0
0
0
% D
% Glu:
0
8
0
8
0
0
0
16
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
0
0
0
0
62
16
47
8
0
0
% G
% His:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
8
0
0
8
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
16
0
0
8
% K
% Leu:
0
47
8
0
0
8
54
8
0
0
0
0
0
0
47
% L
% Met:
8
0
0
8
0
0
0
0
0
8
0
0
0
0
8
% M
% Asn:
24
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% N
% Pro:
8
0
0
0
0
0
8
0
16
16
8
0
8
8
0
% P
% Gln:
0
0
54
62
62
8
0
8
47
0
0
0
8
0
0
% Q
% Arg:
47
16
16
16
24
8
16
0
8
0
0
0
54
16
8
% R
% Ser:
0
8
0
0
8
8
0
39
8
0
47
8
8
31
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% T
% Val:
8
8
8
0
0
47
16
0
0
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _