KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIX6
All Species:
31.49
Human Site:
S240
Identified Species:
57.74
UniProt:
O95475
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95475
NP_031400.2
246
27687
S240
S
A
I
S
I
T
S
S
D
S
E
C
D
I
_
Chimpanzee
Pan troglodytes
XP_522870
514
56142
S508
S
A
I
S
I
T
S
S
D
S
E
C
D
I
_
Rhesus Macaque
Macaca mulatta
XP_001094228
396
43626
S390
S
A
I
S
I
T
S
S
D
S
E
C
D
I
_
Dog
Lupus familis
XP_547840
343
38064
S337
S
A
I
S
I
T
S
S
D
S
E
C
D
I
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ28
246
27723
S240
S
A
I
S
I
T
S
S
D
S
E
C
D
I
_
Rat
Rattus norvegicus
NP_076480
337
35742
S331
S
I
L
S
V
T
S
S
D
S
E
C
D
V
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O93307
246
27619
S240
S
A
I
S
I
T
S
S
D
S
E
C
D
I
_
Frog
Xenopus laevis
P79937
390
42868
M374
G
I
R
A
P
G
P
M
S
G
M
G
M
N
M
Zebra Danio
Brachydanio rerio
NP_957399
245
27632
S239
S
A
I
S
I
T
S
S
D
S
E
C
D
I
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95RW8
487
52401
N278
G
S
T
S
N
G
A
N
D
R
E
E
S
L
S
Honey Bee
Apis mellifera
XP_623764
475
51466
A420
V
T
G
P
L
R
V
A
V
P
S
P
H
T
P
Nematode Worm
Caenorhab. elegans
Q23175
439
49618
E401
P
K
R
A
V
K
T
E
E
V
K
K
E
D
D
Sea Urchin
Strong. purpuratus
XP_781696
324
36468
D292
C
L
L
S
P
H
P
D
D
H
S
P
S
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
61.3
70.5
N.A.
97.9
59
N.A.
N.A.
93.5
20.2
90.6
N.A.
39.2
41.2
35
57.4
Protein Similarity:
100
47.8
61.3
70.8
N.A.
99.1
65.5
N.A.
N.A.
95.9
33.3
94.3
N.A.
43.7
45.4
42.1
63.5
P-Site Identity:
100
100
100
100
N.A.
100
71.4
N.A.
N.A.
100
0
100
N.A.
20
0
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
92.8
N.A.
N.A.
100
6.6
100
N.A.
46.6
13.3
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
0
16
0
0
8
8
0
0
0
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
62
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
77
0
0
0
62
8
8
% D
% Glu:
0
0
0
0
0
0
0
8
8
0
70
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
16
0
8
0
0
16
0
0
0
8
0
8
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
16
54
0
54
0
0
0
0
0
0
0
0
54
0
% I
% Lys:
0
8
0
0
0
8
0
0
0
0
8
8
0
0
0
% K
% Leu:
0
8
16
0
8
0
0
0
0
0
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
8
0
8
0
8
% M
% Asn:
0
0
0
0
8
0
0
8
0
0
0
0
0
8
0
% N
% Pro:
8
0
0
8
16
0
16
0
0
8
0
16
0
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
16
0
0
8
0
0
0
8
0
0
0
0
8
% R
% Ser:
62
8
0
77
0
0
62
62
8
62
16
0
16
0
8
% S
% Thr:
0
8
8
0
0
62
8
0
0
0
0
0
0
8
0
% T
% Val:
8
0
0
0
16
0
8
0
8
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
62
% _