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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIX6
All Species:
20.61
Human Site:
T212
Identified Species:
37.78
UniProt:
O95475
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95475
NP_031400.2
246
27687
T212
L
R
A
E
G
D
G
T
P
E
V
L
G
V
A
Chimpanzee
Pan troglodytes
XP_522870
514
56142
T480
L
R
A
E
G
D
G
T
P
E
V
L
G
V
A
Rhesus Macaque
Macaca mulatta
XP_001094228
396
43626
A362
L
R
A
E
G
D
G
A
S
E
V
L
G
V
A
Dog
Lupus familis
XP_547840
343
38064
T309
L
R
A
E
E
E
G
T
P
E
V
L
G
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ28
246
27723
T212
L
R
S
E
G
E
G
T
P
E
V
L
G
V
A
Rat
Rattus norvegicus
NP_076480
337
35742
S303
H
G
S
A
E
S
P
S
T
A
A
S
P
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O93307
246
27619
G212
L
Q
A
E
E
E
S
G
G
E
A
G
G
A
A
Frog
Xenopus laevis
P79937
390
42868
T346
N
R
A
V
S
Q
G
T
P
Y
N
P
D
G
Q
Zebra Danio
Brachydanio rerio
NP_957399
245
27632
T211
S
L
G
D
D
D
T
T
V
D
R
L
G
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95RW8
487
52401
S250
T
P
S
D
S
S
D
S
D
I
S
L
G
T
H
Honey Bee
Apis mellifera
XP_623764
475
51466
S392
R
L
S
D
G
G
I
S
R
L
S
D
S
L
S
Nematode Worm
Caenorhab. elegans
Q23175
439
49618
L373
K
L
S
I
D
E
I
L
N
I
K
S
E
V
S
Sea Urchin
Strong. purpuratus
XP_781696
324
36468
A264
M
Q
Q
Q
Q
Q
Q
A
L
Q
N
S
S
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
61.3
70.5
N.A.
97.9
59
N.A.
N.A.
93.5
20.2
90.6
N.A.
39.2
41.2
35
57.4
Protein Similarity:
100
47.8
61.3
70.8
N.A.
99.1
65.5
N.A.
N.A.
95.9
33.3
94.3
N.A.
43.7
45.4
42.1
63.5
P-Site Identity:
100
100
86.6
80
N.A.
86.6
0
N.A.
N.A.
40
33.3
33.3
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
100
86.6
86.6
N.A.
100
13.3
N.A.
N.A.
53.3
33.3
46.6
N.A.
33.3
40
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
47
8
0
0
0
16
0
8
16
0
0
16
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
24
16
31
8
0
8
8
0
8
8
0
0
% D
% Glu:
0
0
0
47
24
31
0
0
0
47
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
39
8
47
8
8
0
0
8
62
8
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
8
0
0
16
0
0
16
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
47
24
0
0
0
0
0
8
8
8
0
54
0
8
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
16
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
8
0
39
0
0
8
8
8
0
% P
% Gln:
0
16
8
8
8
16
8
0
0
8
0
0
0
0
8
% Q
% Arg:
8
47
0
0
0
0
0
0
8
0
8
0
0
0
0
% R
% Ser:
8
0
39
0
16
16
8
24
8
0
16
24
16
0
24
% S
% Thr:
8
0
0
0
0
0
8
47
8
0
0
0
0
16
8
% T
% Val:
0
0
0
8
0
0
0
0
8
0
39
0
0
47
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _