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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA1
All Species:
22.73
Human Site:
S1173
Identified Species:
45.45
UniProt:
O95477
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95477
NP_005493.2
2261
254286
S1173
G
L
G
S
D
H
E
S
D
T
L
T
I
D
V
Chimpanzee
Pan troglodytes
XP_001138040
2261
254230
S1173
G
L
G
S
D
H
E
S
D
T
L
T
I
D
V
Rhesus Macaque
Macaca mulatta
XP_001106713
1081
120445
F116
M
S
I
L
T
G
L
F
P
P
T
S
G
T
A
Dog
Lupus familis
XP_538773
2261
253895
S1173
G
L
G
S
D
H
E
S
D
T
L
T
I
D
V
Cat
Felis silvestris
Mouse
Mus musculus
P41233
2261
253955
S1173
G
L
G
S
D
H
E
S
D
T
L
T
I
D
V
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
L1143
F
Q
E
L
D
Q
Q
L
E
R
L
G
L
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
S1177
G
L
G
S
D
H
E
S
D
T
L
T
I
D
V
Chicken
Gallus gallus
NP_989476
2260
254054
S1173
G
L
G
S
D
H
E
S
D
T
L
T
I
D
V
Frog
Xenopus laevis
NP_001089022
2363
267334
D1270
D
P
L
E
Q
E
L
D
G
D
I
S
G
L
T
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
L1253
A
L
Q
P
E
R
V
L
D
G
N
V
E
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
A740
T
T
H
Y
M
D
E
A
E
R
L
G
D
W
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
G918
L
L
A
S
C
N
D
G
A
G
V
I
I
T
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
47
94.9
N.A.
95
50.8
N.A.
89.1
85.4
49.8
51.1
N.A.
N.A.
N.A.
24.9
N.A.
Protein Similarity:
100
99.7
47.5
97.6
N.A.
97.3
67.4
N.A.
94.6
92.6
66.8
67.8
N.A.
N.A.
N.A.
43
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
13.3
N.A.
100
100
0
13.3
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
33.3
N.A.
100
100
13.3
26.6
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
9
9
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
59
9
9
9
59
9
0
0
9
50
0
% D
% Glu:
0
0
9
9
9
9
59
0
17
0
0
0
9
0
0
% E
% Phe:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
50
0
50
0
0
9
0
9
9
17
0
17
17
0
9
% G
% His:
0
0
9
0
0
50
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
9
9
59
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
67
9
17
0
0
17
17
0
0
67
0
9
9
0
% L
% Met:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
9
0
9
0
0
0
0
9
9
0
0
0
0
0
% P
% Gln:
0
9
9
0
9
9
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
17
0
0
0
0
0
% R
% Ser:
0
9
0
59
0
0
0
50
0
0
0
17
0
9
9
% S
% Thr:
9
9
0
0
9
0
0
0
0
50
9
50
0
25
9
% T
% Val:
0
0
0
0
0
0
9
0
0
0
9
9
0
0
59
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _