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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA1
All Species:
22.42
Human Site:
S2225
Identified Species:
44.85
UniProt:
O95477
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95477
NP_005493.2
2261
254286
S2225
V
N
F
A
K
D
Q
S
D
D
D
H
L
K
D
Chimpanzee
Pan troglodytes
XP_001138040
2261
254230
S2225
V
N
F
A
K
D
Q
S
D
D
D
H
L
K
D
Rhesus Macaque
Macaca mulatta
XP_001106713
1081
120445
C1046
V
G
I
P
P
G
E
C
F
G
L
L
G
V
N
Dog
Lupus familis
XP_538773
2261
253895
S2225
V
N
F
A
K
D
Q
S
D
D
D
H
L
K
D
Cat
Felis silvestris
Mouse
Mus musculus
P41233
2261
253955
S2225
V
N
F
A
K
D
Q
S
D
D
D
H
L
K
D
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
G2130
L
Y
F
S
K
D
Q
G
E
E
E
E
G
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
S2230
V
N
F
A
K
D
Q
S
D
D
D
H
L
K
D
Chicken
Gallus gallus
NP_989476
2260
254054
S2224
V
N
F
A
K
D
Q
S
D
D
D
H
T
K
D
Frog
Xenopus laevis
NP_001089022
2363
267334
F2327
L
D
Q
V
F
V
N
F
A
K
Q
Q
T
D
D
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
F2293
L
D
Q
V
F
V
N
F
A
K
Q
Q
S
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
I1669
D
L
G
V
K
D
F
I
L
A
Q
S
S
L
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
D1847
E
G
G
L
S
L
A
D
A
F
G
H
L
E
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
47
94.9
N.A.
95
50.8
N.A.
89.1
85.4
49.8
51.1
N.A.
N.A.
N.A.
24.9
N.A.
Protein Similarity:
100
99.7
47.5
97.6
N.A.
97.3
67.4
N.A.
94.6
92.6
66.8
67.8
N.A.
N.A.
N.A.
43
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
26.6
N.A.
100
93.3
6.6
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
60
N.A.
100
93.3
20
20
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
50
0
0
9
0
25
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
9
17
0
0
0
67
0
9
50
50
50
0
0
9
59
% D
% Glu:
9
0
0
0
0
0
9
0
9
9
9
9
0
9
17
% E
% Phe:
0
0
59
0
17
0
9
17
9
9
0
0
0
0
0
% F
% Gly:
0
17
17
0
0
9
0
9
0
9
9
0
17
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
59
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
67
0
0
0
0
17
0
0
0
50
0
% K
% Leu:
25
9
0
9
0
9
0
0
9
0
9
9
50
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
50
0
0
0
0
17
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
17
0
0
0
59
0
0
0
25
17
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
0
0
9
9
0
0
50
0
0
0
9
17
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% T
% Val:
59
0
0
25
0
17
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _