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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA1
All Species:
6.06
Human Site:
T1399
Identified Species:
12.12
UniProt:
O95477
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95477
NP_005493.2
2261
254286
T1399
S
N
D
A
P
E
D
T
G
T
L
E
L
L
N
Chimpanzee
Pan troglodytes
XP_001138040
2261
254230
T1399
S
N
D
A
P
E
D
T
G
T
L
E
L
L
N
Rhesus Macaque
Macaca mulatta
XP_001106713
1081
120445
S327
K
E
D
S
V
S
Q
S
S
S
D
A
G
L
G
Dog
Lupus familis
XP_538773
2261
253895
M1399
S
N
D
A
P
E
D
M
S
T
Q
E
L
L
N
Cat
Felis silvestris
Mouse
Mus musculus
P41233
2261
253955
M1399
S
N
D
A
P
E
D
M
G
T
Q
E
L
L
N
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
N1360
A
S
I
L
A
S
G
N
W
T
P
D
S
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
A1404
S
N
D
A
P
G
D
A
N
T
Q
K
L
L
N
Chicken
Gallus gallus
NP_989476
2260
254054
A1399
S
N
D
A
P
E
D
A
G
T
Q
K
L
L
D
Frog
Xenopus laevis
NP_001089022
2363
267334
E1502
S
N
E
H
P
G
N
E
Q
M
A
T
F
S
N
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
P1465
S
N
E
Q
P
S
H
P
K
M
K
H
F
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
K951
Q
F
I
S
I
M
R
K
K
F
L
Y
S
R
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
A1129
H
N
G
T
C
Q
H
A
G
P
I
Y
I
N
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
47
94.9
N.A.
95
50.8
N.A.
89.1
85.4
49.8
51.1
N.A.
N.A.
N.A.
24.9
N.A.
Protein Similarity:
100
99.7
47.5
97.6
N.A.
97.3
67.4
N.A.
94.6
92.6
66.8
67.8
N.A.
N.A.
N.A.
43
N.A.
P-Site Identity:
100
100
13.3
80
N.A.
86.6
6.6
N.A.
66.6
73.3
26.6
20
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
33.3
80
N.A.
86.6
33.3
N.A.
73.3
86.6
40
33.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
50
9
0
0
25
0
0
9
9
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
59
0
0
0
50
0
0
0
9
9
0
0
9
% D
% Glu:
0
9
17
0
0
42
0
9
0
0
0
34
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
9
0
0
17
0
0
% F
% Gly:
0
0
9
0
0
17
9
0
42
0
0
0
9
0
9
% G
% His:
9
0
0
9
0
0
17
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
17
0
9
0
0
0
0
0
9
0
9
9
0
% I
% Lys:
9
0
0
0
0
0
0
9
17
0
9
17
0
0
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
0
25
0
50
59
0
% L
% Met:
0
0
0
0
0
9
0
17
0
17
0
0
0
0
0
% M
% Asn:
0
75
0
0
0
0
9
9
9
0
0
0
0
9
50
% N
% Pro:
0
0
0
0
67
0
0
9
0
9
9
0
0
9
0
% P
% Gln:
9
0
0
9
0
9
9
0
9
0
34
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
9
% R
% Ser:
67
9
0
17
0
25
0
9
17
9
0
0
17
9
9
% S
% Thr:
0
0
0
9
0
0
0
17
0
59
0
9
0
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _