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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H6PD
All Species:
12.73
Human Site:
S317
Identified Species:
23.33
UniProt:
O95479
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95479
NP_004276.2
791
88893
S317
V
G
Q
Y
Q
S
Y
S
E
Q
V
R
R
E
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099298
791
88822
S317
V
G
Q
Y
Q
S
Y
S
E
Q
V
R
R
E
L
Dog
Lupus familis
XP_546762
789
89091
S314
L
G
Q
Y
Q
A
Y
S
R
Q
V
R
R
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFX1
789
88892
S314
L
G
Q
Y
Q
A
Y
S
G
Q
V
R
R
E
L
Rat
Rattus norvegicus
P05370
515
59357
L75
V
G
Y
A
R
S
R
L
T
V
D
D
I
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513087
312
34898
Chicken
Gallus gallus
XP_425746
782
88274
A309
V
G
Q
Y
Q
A
Y
A
S
H
V
Q
E
E
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697820
781
88168
N314
V
G
Q
Y
Q
A
Y
N
G
E
V
Q
A
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12646
524
60412
I84
S
M
L
T
V
D
S
I
K
E
Q
C
L
P
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27464
522
60197
K81
R
S
D
L
T
V
F
K
L
R
E
S
F
E
K
Sea Urchin
Strong. purpuratus
XP_795087
853
96259
V379
I
G
Q
Y
E
S
Y
V
D
E
W
R
E
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150684
507
57610
F67
Q
S
G
E
V
H
I
F
G
Y
A
R
S
N
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11412
505
57503
V65
E
E
D
L
K
S
R
V
L
P
H
L
K
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
84.8
N.A.
83.4
23.1
N.A.
30.5
69.2
N.A.
53
N.A.
22.1
N.A.
22.8
39.9
Protein Similarity:
100
N.A.
98.4
91.6
N.A.
90.3
38.4
N.A.
35.4
82.3
N.A.
71.8
N.A.
37.9
N.A.
39.3
55.9
P-Site Identity:
100
N.A.
100
73.3
N.A.
80
20
N.A.
0
60
N.A.
60
N.A.
0
N.A.
6.6
46.6
P-Site Similarity:
100
N.A.
100
86.6
N.A.
93.3
26.6
N.A.
0
80
N.A.
86.6
N.A.
13.3
N.A.
20
80
Percent
Protein Identity:
N.A.
25.2
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
39.7
N.A.
N.A.
36.7
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
31
0
8
0
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
16
0
0
8
0
0
8
0
8
8
0
0
0
% D
% Glu:
8
8
0
8
8
0
0
0
16
24
8
0
16
62
0
% E
% Phe:
0
0
0
0
0
0
8
8
0
0
0
0
8
0
0
% F
% Gly:
0
62
8
0
0
0
0
0
24
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
8
8
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
8
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
8
0
0
8
8
0
0
0
8
8
16
% K
% Leu:
16
0
8
16
0
0
0
8
16
0
0
8
8
0
47
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% P
% Gln:
8
0
54
0
47
0
0
0
0
31
8
16
0
0
8
% Q
% Arg:
8
0
0
0
8
0
16
0
8
8
0
47
31
8
0
% R
% Ser:
8
16
0
0
0
39
8
31
8
0
0
8
8
0
0
% S
% Thr:
0
0
0
8
8
0
0
0
8
0
0
0
0
0
0
% T
% Val:
39
0
0
0
16
8
0
16
0
8
47
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
8
54
0
0
54
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _