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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H6PD
All Species:
19.39
Human Site:
S721
Identified Species:
35.56
UniProt:
O95479
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95479
NP_004276.2
791
88893
S721
Q
L
V
V
L
T
T
S
P
S
Q
P
H
R
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099298
791
88822
S721
Q
L
V
V
L
T
T
S
P
S
Q
P
H
R
R
Dog
Lupus familis
XP_546762
789
89091
S719
Q
P
V
V
L
T
R
S
P
Y
K
P
H
Q
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFX1
789
88892
S719
Q
L
V
V
L
T
E
S
P
F
R
P
H
Q
R
Rat
Rattus norvegicus
P05370
515
59357
R454
G
S
Q
M
H
F
V
R
S
D
E
L
R
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513087
312
34898
V251
D
A
A
A
A
S
M
V
A
V
P
E
S
I
W
Chicken
Gallus gallus
XP_425746
782
88274
S712
Q
A
V
V
L
T
E
S
P
V
K
P
H
Q
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697820
781
88168
S711
R
L
V
T
L
T
E
S
P
I
K
P
H
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P12646
524
60412
L463
H
F
V
R
S
D
E
L
R
E
A
W
R
I
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27464
522
60197
V461
M
G
S
Q
I
N
F
V
R
T
D
E
L
E
Y
Sea Urchin
Strong. purpuratus
XP_795087
853
96259
G781
N
F
V
L
F
S
D
G
A
V
Q
S
S
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001150684
507
57610
R446
G
D
Q
Q
H
F
V
R
R
D
E
L
Q
A
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11412
505
57503
W444
D
D
E
L
D
I
S
W
G
I
F
T
P
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
84.8
N.A.
83.4
23.1
N.A.
30.5
69.2
N.A.
53
N.A.
22.1
N.A.
22.8
39.9
Protein Similarity:
100
N.A.
98.4
91.6
N.A.
90.3
38.4
N.A.
35.4
82.3
N.A.
71.8
N.A.
37.9
N.A.
39.3
55.9
P-Site Identity:
100
N.A.
100
66.6
N.A.
73.3
0
N.A.
0
66.6
N.A.
60
N.A.
6.6
N.A.
0
13.3
P-Site Similarity:
100
N.A.
100
80
N.A.
86.6
13.3
N.A.
6.6
80
N.A.
80
N.A.
6.6
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
25.2
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
39.7
N.A.
N.A.
36.7
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
8
8
0
0
0
16
0
8
0
0
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
16
0
0
8
8
8
0
0
16
8
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
31
0
0
8
16
16
0
16
0
% E
% Phe:
0
16
0
0
8
16
8
0
0
8
8
0
0
0
8
% F
% Gly:
16
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% G
% His:
8
0
0
0
16
0
0
0
0
0
0
0
47
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
16
0
0
0
16
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
24
0
0
0
0
% K
% Leu:
0
31
0
16
47
0
0
8
0
0
0
16
8
8
8
% L
% Met:
8
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
47
0
8
47
8
0
8
% P
% Gln:
39
0
16
16
0
0
0
0
0
0
24
0
8
31
0
% Q
% Arg:
8
0
0
8
0
0
8
16
24
0
8
0
16
16
47
% R
% Ser:
0
8
8
0
8
16
8
47
8
16
0
8
16
8
0
% S
% Thr:
0
0
0
8
0
47
16
0
0
8
0
8
0
0
0
% T
% Val:
0
0
62
39
0
0
16
16
0
24
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _