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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLDN9
All Species:
18.31
Human Site:
Y216
Identified Species:
50.35
UniProt:
O95484
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95484
NP_066192.1
217
22848
Y216
S
G
L
D
K
R
D
Y
V
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_523276
220
23303
T216
R
G
P
S
E
Y
P
T
K
N
Y
V
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001088610
217
22876
Y216
S
G
L
D
K
R
D
Y
V
_
_
_
_
_
_
Dog
Lupus familis
XP_547169
217
22864
Y216
S
G
L
D
K
R
D
Y
V
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0S7
217
22966
Y216
S
G
L
D
K
R
D
Y
V
_
_
_
_
_
_
Rat
Rattus norvegicus
Q63400
219
23296
Y218
T
A
Y
D
R
K
D
Y
V
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989533
214
23072
Frog
Xenopus laevis
NP_001087400
213
22866
Zebra Danio
Brachydanio rerio
Q9YH91
208
22187
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.9
99
96.7
N.A.
95.8
63
N.A.
N.A.
66.8
65.4
60.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
83.6
100
99.5
N.A.
97.2
78
N.A.
N.A.
82.9
85.7
77.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
8.3
100
100
N.A.
100
44.4
N.A.
N.A.
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
25
100
100
N.A.
100
77.7
N.A.
N.A.
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
56
0
0
56
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
56
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
45
12
0
0
12
0
0
0
0
0
0
% K
% Leu:
0
0
45
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% N
% Pro:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
0
0
12
45
0
0
0
0
0
0
0
0
0
% R
% Ser:
45
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
12
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
56
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
12
0
56
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
56
56
56
67
67
67
% _