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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24A All Species: 22.73
Human Site: S74 Identified Species: 38.46
UniProt: O95486 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95486 NP_068817.1 1093 119749 S74 L N P V S G Q S N Y G G S Q G
Chimpanzee Pan troglodytes XP_527165 1093 119711 S74 L N P V S G Q S N Y G G S Q G
Rhesus Macaque Macaca mulatta XP_001109620 1093 119674 S74 L N P V S G Q S N Y G G S Q G
Dog Lupus familis XP_850736 1100 120445 S74 L N P V S G Q S N Y G G S Q T
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 S74 L N P F S A Q S N Y G G S Q G
Rat Rattus norvegicus NP_001099250 1089 118849 S74 L N P F S A Q S N Y G G S Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510651 1234 134485 S179 Y G G P Q T V S A L N N Y Q G
Chicken Gallus gallus XP_414630 1100 120006 N77 S Q N V S Q F N S Y Q G P G Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001340708 1097 118527 S77 T H S P L P A S P N H R P V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394884 843 95632
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784354 1353 146633 P140 G Q Y L G P P P P G G R P P Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFU0 1038 113942 P74 P P V G T M R P G Q P S P F V
Baker's Yeast Sacchar. cerevisiae P40482 926 103617
Red Bread Mold Neurospora crassa Q7S4P3 950 103512
Conservation
Percent
Protein Identity: 100 99.4 97.7 92.1 N.A. 88.3 88.2 N.A. 69.1 74 N.A. 59.5 N.A. N.A. 44.7 N.A. 28.7
Protein Similarity: 100 99.8 98.2 94.2 N.A. 92.4 92 N.A. 76.2 83 N.A. 71.4 N.A. N.A. 59.4 N.A. 43
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 20 26.6 N.A. 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 20 40 N.A. 13.3 N.A. N.A. 0 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 34.5 29.7 31.7
Protein Similarity: N.A. N.A. N.A. 53.5 48.2 49.7
P-Site Identity: N.A. N.A. N.A. 0 0 0
P-Site Similarity: N.A. N.A. N.A. 13.3 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 15 8 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 15 0 0 8 0 0 0 0 0 0 8 0 % F
% Gly: 8 8 8 8 8 29 0 0 8 8 50 50 0 8 43 % G
% His: 0 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 43 0 0 8 8 0 0 0 0 8 0 0 0 0 8 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 43 8 0 0 0 0 8 43 8 8 8 0 0 0 % N
% Pro: 8 8 43 15 0 15 8 15 15 0 8 0 29 8 0 % P
% Gln: 0 15 0 0 8 8 43 0 0 8 8 0 0 50 15 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 15 0 0 0 % R
% Ser: 8 0 8 0 50 0 0 58 8 0 0 8 43 0 0 % S
% Thr: 8 0 0 0 8 8 0 0 0 0 0 0 0 0 8 % T
% Val: 0 0 8 36 0 0 8 0 0 0 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 0 0 0 0 0 0 50 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _