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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24A All Species: 10.61
Human Site: T225 Identified Species: 17.95
UniProt: O95486 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95486 NP_068817.1 1093 119749 T225 P P P V R A L T P L T S S Y R
Chimpanzee Pan troglodytes XP_527165 1093 119711 T225 P P P V R A L T P L T S S Y R
Rhesus Macaque Macaca mulatta XP_001109620 1093 119674 M225 P P P I R A L M P Q T S S Y R
Dog Lupus familis XP_850736 1100 120445 T232 P L P V R A L T P Q K S S Q R
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 A223 P P P S R G P A P Q K T P P R
Rat Rattus norvegicus NP_001099250 1089 118849 P222 G P P P S R G P V P Q K T P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510651 1234 134485 P331 P P I R P L A P P R G S P N S
Chicken Gallus gallus XP_414630 1100 120006 S232 G P P L I R P S T V T A G A P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001340708 1097 118527 T225 A G A P P T S T V L P P P R A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394884 843 95632 D26 R Y S E S Y S D Q M N H I N N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784354 1353 146633 L359 P F R D L S H L P V I Q S S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFU0 1038 113942 A218 P S K Q V L Q A P T P F Q T S
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 L109 P V Q M G T P L Q Q Q Q Q P M
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 Y133 Y Q A P D P Y Y S Q G V P P A
Conservation
Percent
Protein Identity: 100 99.4 97.7 92.1 N.A. 88.3 88.2 N.A. 69.1 74 N.A. 59.5 N.A. N.A. 44.7 N.A. 28.7
Protein Similarity: 100 99.8 98.2 94.2 N.A. 92.4 92 N.A. 76.2 83 N.A. 71.4 N.A. N.A. 59.4 N.A. 43
P-Site Identity: 100 100 80 73.3 N.A. 40 13.3 N.A. 26.6 20 N.A. 13.3 N.A. N.A. 0 N.A. 20
P-Site Similarity: 100 100 86.6 73.3 N.A. 46.6 20 N.A. 26.6 46.6 N.A. 13.3 N.A. N.A. 6.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 34.5 29.7 31.7
Protein Similarity: N.A. N.A. N.A. 53.5 48.2 49.7
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 0
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 15 0 0 29 8 15 0 0 0 8 0 8 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 8 0 0 8 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 15 8 0 0 8 8 8 0 0 0 15 0 8 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 8 8 8 0 0 0 0 0 8 0 8 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 0 0 15 8 0 0 0 % K
% Leu: 0 8 0 8 8 15 29 15 0 22 0 0 0 0 0 % L
% Met: 0 0 0 8 0 0 0 8 0 8 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 15 8 % N
% Pro: 65 50 50 22 15 8 22 15 58 8 15 8 29 29 15 % P
% Gln: 0 8 8 8 0 0 8 0 15 36 15 15 15 8 0 % Q
% Arg: 8 0 8 8 36 15 0 0 0 8 0 0 0 8 36 % R
% Ser: 0 8 8 8 15 8 15 8 8 0 0 36 36 8 15 % S
% Thr: 0 0 0 0 0 15 0 29 8 8 29 8 8 8 0 % T
% Val: 0 8 0 22 8 0 0 0 15 15 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 8 0 0 0 8 8 8 0 0 0 0 0 22 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _