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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC24A
All Species:
20.61
Human Site:
T274
Identified Species:
34.87
UniProt:
O95486
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95486
NP_068817.1
1093
119749
T274
E
G
G
G
L
L
A
T
P
Q
L
T
N
K
N
Chimpanzee
Pan troglodytes
XP_527165
1093
119711
T274
E
G
G
G
L
L
A
T
P
Q
L
T
N
K
N
Rhesus Macaque
Macaca mulatta
XP_001109620
1093
119674
T274
E
G
G
G
L
L
A
T
P
Q
L
T
N
K
N
Dog
Lupus familis
XP_850736
1100
120445
T281
E
G
G
G
F
L
A
T
P
Q
Y
A
N
K
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3U2P1
1090
118764
T272
E
G
G
G
F
L
A
T
P
Q
L
V
N
Q
N
Rat
Rattus norvegicus
NP_001099250
1089
118849
T271
E
G
G
G
F
L
A
T
P
Q
L
V
N
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510651
1234
134485
A380
E
G
G
G
F
M
G
A
S
H
P
P
N
Q
N
Chicken
Gallus gallus
XP_414630
1100
120006
P281
G
G
G
L
M
A
T
P
H
P
S
A
P
A
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001340708
1097
118527
Q274
G
S
G
Y
P
S
L
Q
P
G
Y
S
T
A
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394884
843
95632
D75
R
Y
P
E
S
Y
P
D
Q
I
N
H
L
N
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784354
1353
146633
P408
P
E
E
F
T
F
D
P
V
T
K
T
Y
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SFU0
1038
113942
V267
Y
A
P
P
P
S
N
V
Q
G
L
T
E
D
F
Baker's Yeast
Sacchar. cerevisiae
P40482
926
103617
P158
I
T
D
L
T
L
P
P
P
P
L
V
I
P
P
Red Bread Mold
Neurospora crassa
Q7S4P3
950
103512
L182
T
R
G
L
V
N
Q
L
Y
P
T
D
L
L
N
Conservation
Percent
Protein Identity:
100
99.4
97.7
92.1
N.A.
88.3
88.2
N.A.
69.1
74
N.A.
59.5
N.A.
N.A.
44.7
N.A.
28.7
Protein Similarity:
100
99.8
98.2
94.2
N.A.
92.4
92
N.A.
76.2
83
N.A.
71.4
N.A.
N.A.
59.4
N.A.
43
P-Site Identity:
100
100
100
80
N.A.
80
80
N.A.
40
20
N.A.
13.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
86.6
86.6
N.A.
53.3
26.6
N.A.
20
N.A.
N.A.
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
29.7
31.7
Protein Similarity:
N.A.
N.A.
N.A.
53.5
48.2
49.7
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
43
8
0
0
0
15
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
8
8
0
0
0
8
0
8
8
% D
% Glu:
50
8
8
8
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
8
29
8
0
0
0
0
0
0
0
0
8
% F
% Gly:
15
58
72
50
0
0
8
0
0
15
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
0
29
0
% K
% Leu:
0
0
0
22
22
50
8
8
0
0
50
0
15
8
0
% L
% Met:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
0
8
0
50
8
72
% N
% Pro:
8
0
15
8
15
0
15
22
58
22
8
8
8
8
8
% P
% Gln:
0
0
0
0
0
0
8
8
15
43
0
0
0
22
8
% Q
% Arg:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
8
15
0
0
8
0
8
8
0
0
0
% S
% Thr:
8
8
0
0
15
0
8
43
0
8
8
36
8
0
0
% T
% Val:
0
0
0
0
8
0
0
8
8
0
0
22
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
8
0
8
0
0
8
0
15
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _