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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24A All Species: 31.52
Human Site: Y714 Identified Species: 53.33
UniProt: O95486 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95486 NP_068817.1 1093 119749 Y714 R Y S A G S V Y Y Y P S Y H H
Chimpanzee Pan troglodytes XP_527165 1093 119711 Y714 R Y S A G S V Y Y Y P S Y H H
Rhesus Macaque Macaca mulatta XP_001109620 1093 119674 Y714 R Y S A G S V Y Y Y P S Y H H
Dog Lupus familis XP_850736 1100 120445 Y721 R Y S A G S V Y Y Y P S Y H H
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 Y711 R Y S A G S V Y Y Y P S Y H H
Rat Rattus norvegicus NP_001099250 1089 118849 Y710 R Y S A G S V Y Y Y P S Y H H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510651 1234 134485 Y855 R Y S A G S V Y Y Y P S Y H H
Chicken Gallus gallus XP_414630 1100 120006 Y721 R Y S A G S V Y Y Y Q S Y H H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001340708 1097 118527 F718 R Y S A G S V F Y Y P S Y H T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394884 843 95632 V480 R A S K P Q H V E T L D R I L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784354 1353 146633 D473 Q T I I D N L D K M P G D A R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFU0 1038 113942 H674 V H G D K L R H E L A R D L T
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 S563 T V M R A R G S T G L R M S R
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 L587 A S E F S D Y L S S E I G L E
Conservation
Percent
Protein Identity: 100 99.4 97.7 92.1 N.A. 88.3 88.2 N.A. 69.1 74 N.A. 59.5 N.A. N.A. 44.7 N.A. 28.7
Protein Similarity: 100 99.8 98.2 94.2 N.A. 92.4 92 N.A. 76.2 83 N.A. 71.4 N.A. N.A. 59.4 N.A. 43
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 N.A. 86.6 N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 N.A. 93.3 N.A. N.A. 13.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 34.5 29.7 31.7
Protein Similarity: N.A. N.A. N.A. 53.5 48.2 49.7
P-Site Identity: N.A. N.A. N.A. 0 0 0
P-Site Similarity: N.A. N.A. N.A. 13.3 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 65 8 0 0 0 0 0 8 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 8 8 0 8 0 0 0 8 15 0 0 % D
% Glu: 0 0 8 0 0 0 0 0 15 0 8 0 0 0 8 % E
% Phe: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 65 0 8 0 0 8 0 8 8 0 0 % G
% His: 0 8 0 0 0 0 8 8 0 0 0 0 0 65 58 % H
% Ile: 0 0 8 8 0 0 0 0 0 0 0 8 0 8 0 % I
% Lys: 0 0 0 8 8 0 0 0 8 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 8 8 8 0 8 15 0 0 15 8 % L
% Met: 0 0 8 0 0 0 0 0 0 8 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 8 0 0 0 0 0 65 0 0 0 0 % P
% Gln: 8 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % Q
% Arg: 72 0 0 8 0 8 8 0 0 0 0 15 8 0 15 % R
% Ser: 0 8 72 0 8 65 0 8 8 8 0 65 0 8 0 % S
% Thr: 8 8 0 0 0 0 0 0 8 8 0 0 0 0 15 % T
% Val: 8 8 0 0 0 0 65 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 65 0 0 0 0 8 58 65 65 0 0 65 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _