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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC24B
All Species:
17.88
Human Site:
S1254
Identified Species:
30.26
UniProt:
O95487
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95487
NP_001036199.1
1268
137418
S1254
D
R
T
E
A
A
F
S
Y
Y
E
F
L
L
H
Chimpanzee
Pan troglodytes
XP_001136519
1173
128734
L1164
A
F
S
Y
Y
E
F
L
L
H
V
Q
Q
Q
I
Rhesus Macaque
Macaca mulatta
XP_001087955
1263
137118
S1249
D
R
T
E
A
A
F
S
Y
Y
E
F
L
L
H
Dog
Lupus familis
XP_545021
1258
136639
S1244
D
R
T
E
A
A
F
S
Y
Y
E
F
L
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3U2P1
1090
118764
L1081
A
L
S
Y
Y
E
F
L
L
H
I
Q
Q
Q
V
Rat
Rattus norvegicus
NP_001099944
1242
134697
S1228
D
R
T
E
A
A
L
S
Y
Y
E
F
L
I
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506149
1278
138146
G1269
L
Q
G
G
G
R
W
G
A
F
R
D
R
S
A
Chicken
Gallus gallus
NP_001026306
1234
134555
S1220
D
R
T
E
A
A
F
S
Y
Y
E
F
L
L
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001340708
1097
118527
L1088
A
L
S
Y
Y
E
F
L
L
H
L
Q
Q
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394884
843
95632
F834
N
S
L
S
Y
Y
E
F
L
Q
H
L
K
T
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784354
1353
146633
R1311
M
S
T
K
L
D
T
R
V
F
A
M
E
M
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SFU0
1038
113942
L1029
S
G
Y
V
D
W
I
L
Q
L
H
R
Q
V
Q
Baker's Yeast
Sacchar. cerevisiae
P40482
926
103617
L917
N
E
S
Y
R
E
F
L
Q
I
M
K
A
R
I
Red Bread Mold
Neurospora crassa
Q7S4P3
950
103512
M941
G
M
S
F
Q
Q
W
M
G
M
L
R
E
K
V
Conservation
Percent
Protein Identity:
100
86.2
97.7
92.6
N.A.
54.3
81.7
N.A.
71
74.2
N.A.
51.4
N.A.
N.A.
39.9
N.A.
39.8
Protein Similarity:
100
87.5
98.8
95.5
N.A.
66.6
87.4
N.A.
78.7
81.2
N.A.
63.6
N.A.
N.A.
52.1
N.A.
54.4
P-Site Identity:
100
6.6
100
100
N.A.
6.6
86.6
N.A.
0
100
N.A.
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
20
100
100
N.A.
20
93.3
N.A.
20
100
N.A.
20
N.A.
N.A.
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.9
28
30.6
Protein Similarity:
N.A.
N.A.
N.A.
48.4
43
43.8
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
0
0
36
36
0
0
8
0
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
36
0
0
0
8
8
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
8
0
36
0
29
8
0
0
0
36
0
15
0
0
% E
% Phe:
0
8
0
8
0
0
58
8
0
15
0
36
0
0
8
% F
% Gly:
8
8
8
8
8
0
0
8
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
22
15
0
0
0
36
% H
% Ile:
0
0
0
0
0
0
8
0
0
8
8
0
0
8
15
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
8
8
8
0
% K
% Leu:
8
15
8
0
8
0
8
36
29
8
15
8
36
29
0
% L
% Met:
8
8
0
0
0
0
0
8
0
8
8
8
0
8
0
% M
% Asn:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
8
8
0
0
15
8
0
22
29
22
15
% Q
% Arg:
0
36
0
0
8
8
0
8
0
0
8
15
8
8
0
% R
% Ser:
8
15
36
8
0
0
0
36
0
0
0
0
0
8
8
% S
% Thr:
0
0
43
0
0
0
8
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
8
0
0
0
0
8
0
8
0
0
8
15
% V
% Trp:
0
0
0
0
0
8
15
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
29
29
8
0
0
36
36
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _