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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24B All Species: 4.24
Human Site: S325 Identified Species: 7.18
UniProt: O95487 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95487 NP_001036199.1 1268 137418 S325 L S G S S G S S S T R T P P T
Chimpanzee Pan troglodytes XP_001136519 1173 128734 G260 N L I R N H T G S L A V A N N
Rhesus Macaque Macaca mulatta XP_001087955 1263 137118 R323 L S G S S S T R T P P T A N H
Dog Lupus familis XP_545021 1258 136639 T316 K S S P V V S T V L G A S S T
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 A179 Y V S S G D P A L Q T S F K K
Rat Rattus norvegicus NP_001099944 1242 134697 T311 V L P G P S S T R M P P A P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506149 1278 138146 A313 I N N Q A S S A P T P L S S T
Chicken Gallus gallus NP_001026306 1234 134555 S311 A S S A L I S S V R T P A P G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001340708 1097 118527 P172 P P P S T I A P P P F A A A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394884 843 95632
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784354 1353 146633 R326 Q V S P D V F R S T L N A I P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFU0 1038 113942 G127 T T Q N P P Q G P P P P Q T L
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 Q15 V Y P Q A Q L Q Y G Q N A T P
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 P39 A Y G S P A S P P P A A A S Q
Conservation
Percent
Protein Identity: 100 86.2 97.7 92.6 N.A. 54.3 81.7 N.A. 71 74.2 N.A. 51.4 N.A. N.A. 39.9 N.A. 39.8
Protein Similarity: 100 87.5 98.8 95.5 N.A. 66.6 87.4 N.A. 78.7 81.2 N.A. 63.6 N.A. N.A. 52.1 N.A. 54.4
P-Site Identity: 100 6.6 40 20 N.A. 6.6 13.3 N.A. 20 26.6 N.A. 6.6 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 20 53.3 26.6 N.A. 20 33.3 N.A. 46.6 33.3 N.A. 20 N.A. N.A. 0 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 31.9 28 30.6
Protein Similarity: N.A. N.A. N.A. 48.4 43 43.8
P-Site Identity: N.A. N.A. N.A. 0 0 20
P-Site Similarity: N.A. N.A. N.A. 13.3 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 8 15 8 8 15 0 0 15 22 58 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 8 0 8 0 0 % F
% Gly: 0 0 22 8 8 8 0 15 0 8 8 0 0 0 8 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 8 0 0 15 0 0 0 0 0 0 0 8 0 % I
% Lys: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 8 % K
% Leu: 15 15 0 0 8 0 8 0 8 15 8 8 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 8 8 8 8 8 0 0 0 0 0 0 15 0 15 8 % N
% Pro: 8 8 22 15 22 8 8 15 29 29 29 22 8 22 22 % P
% Gln: 8 0 8 15 0 8 8 8 0 8 8 0 8 0 8 % Q
% Arg: 0 0 0 8 0 0 0 15 8 8 8 0 0 0 0 % R
% Ser: 0 29 29 36 15 22 43 15 22 0 0 8 15 22 8 % S
% Thr: 8 8 0 0 8 0 15 15 8 22 15 15 0 15 22 % T
% Val: 15 15 0 0 8 15 0 0 15 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 15 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _