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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24B All Species: 8.79
Human Site: S400 Identified Species: 14.87
UniProt: O95487 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95487 NP_001036199.1 1268 137418 S400 S S T T S S A S P M P N S Y D
Chimpanzee Pan troglodytes XP_001136519 1173 128734 N335 V Q Y G E Y V N N Q A S S A P
Rhesus Macaque Macaca mulatta XP_001087955 1263 137118 M397 T T S S A S P M P N S Y D A L
Dog Lupus familis XP_545021 1258 136639 S390 E A G V D S S S T T S S A S P
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 G253 I T S N A N N G S T A A H N T
Rat Rattus norvegicus NP_001099944 1242 134697 P385 S T T S S A S P L P N S Y D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506149 1278 138146 T400 S P A P A P S T P Q P A K T S
Chicken Gallus gallus NP_001026306 1234 134555 S386 S S T T S S A S P V L N N Y D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001340708 1097 118527 G260 D A G P Y H L G Q M S R P V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394884 843 95632
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784354 1353 146633 L437 I A P S E Y M L R P P Q P A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFU0 1038 113942 G201 T P S Y P G V G G S Q P S F P
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 P89 D M H L H N V P L V D P N A Y
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 Y113 Y G A P T T P Y G A P Q P A V
Conservation
Percent
Protein Identity: 100 86.2 97.7 92.6 N.A. 54.3 81.7 N.A. 71 74.2 N.A. 51.4 N.A. N.A. 39.9 N.A. 39.8
Protein Similarity: 100 87.5 98.8 95.5 N.A. 66.6 87.4 N.A. 78.7 81.2 N.A. 63.6 N.A. N.A. 52.1 N.A. 54.4
P-Site Identity: 100 6.6 13.3 13.3 N.A. 0 20 N.A. 20 80 N.A. 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 20 46.6 40 N.A. 26.6 53.3 N.A. 40 93.3 N.A. 13.3 N.A. N.A. 0 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 31.9 28 30.6
Protein Similarity: N.A. N.A. N.A. 48.4 43 43.8
P-Site Identity: N.A. N.A. N.A. 6.6 0 6.6
P-Site Similarity: N.A. N.A. N.A. 26.6 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 22 15 0 22 8 15 0 0 8 15 15 8 36 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 0 0 8 0 0 0 0 0 8 0 8 8 15 % D
% Glu: 8 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 8 15 8 0 8 0 22 15 0 0 0 0 0 8 % G
% His: 0 0 8 0 8 8 0 0 0 0 0 0 8 0 0 % H
% Ile: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 0 8 0 0 8 8 15 0 8 0 0 0 8 % L
% Met: 0 8 0 0 0 0 8 8 0 15 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 15 8 8 8 8 8 15 15 8 0 % N
% Pro: 0 15 8 22 8 8 15 15 29 15 29 15 22 0 22 % P
% Gln: 0 8 0 0 0 0 0 0 8 15 8 15 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % R
% Ser: 29 15 22 22 22 29 22 22 8 8 22 22 22 8 8 % S
% Thr: 15 22 22 15 8 8 0 8 8 15 0 0 0 8 8 % T
% Val: 8 0 0 8 0 0 22 0 0 15 0 0 0 8 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 8 8 15 0 8 0 0 0 8 8 15 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _