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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24B All Species: 11.82
Human Site: S419 Identified Species: 20
UniProt: O95487 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95487 NP_001036199.1 1268 137418 S419 G S Y P D M L S S S A S S P A
Chimpanzee Pan troglodytes XP_001136519 1173 128734 E354 S T S D D E E E E E E D E E A
Rhesus Macaque Macaca mulatta XP_001087955 1263 137118 S416 Y P D M L S S S A S S P A P D
Dog Lupus familis XP_545021 1258 136639 S409 Y D A L E G G S Y P D M L S S
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 T272 E G G G F L A T P Q L V N Q N
Rat Rattus norvegicus NP_001099944 1242 134697 S404 S Y P D M H S S S A S S P V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506149 1278 138146 P419 Y G Y P T L Q P G Y Q N A A P
Chicken Gallus gallus NP_001026306 1234 134555 S405 G G Y P E T R S V T N S P V P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001340708 1097 118527 T279 S L Q P G Y S T A Q G Y T P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394884 843 95632 S25 K R Y S E S Y S D Q M N H I N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784354 1353 146633 V456 L D V S F S A V E S G Y L S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SFU0 1038 113942 T220 K Q V L Q A P T P F Q T S Q G
Baker's Yeast Sacchar. cerevisiae P40482 926 103617 P108 V P V Q M G T P L Q Q Q Q Q P
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 Y132 G Y Q A P D P Y Y S Q G V P P
Conservation
Percent
Protein Identity: 100 86.2 97.7 92.6 N.A. 54.3 81.7 N.A. 71 74.2 N.A. 51.4 N.A. N.A. 39.9 N.A. 39.8
Protein Similarity: 100 87.5 98.8 95.5 N.A. 66.6 87.4 N.A. 78.7 81.2 N.A. 63.6 N.A. N.A. 52.1 N.A. 54.4
P-Site Identity: 100 13.3 20 6.6 N.A. 0 20 N.A. 13.3 33.3 N.A. 13.3 N.A. N.A. 13.3 N.A. 6.6
P-Site Similarity: 100 20 40 20 N.A. 20 33.3 N.A. 33.3 46.6 N.A. 33.3 N.A. N.A. 26.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 31.9 28 30.6
Protein Similarity: N.A. N.A. N.A. 48.4 43 43.8
P-Site Identity: N.A. N.A. N.A. 6.6 0 20
P-Site Similarity: N.A. N.A. N.A. 20 0 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 8 15 0 15 8 8 0 15 8 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 8 15 15 8 0 0 8 0 8 8 0 0 8 % D
% Glu: 8 0 0 0 22 8 8 8 15 8 8 0 8 8 0 % E
% Phe: 0 0 0 0 15 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 22 22 8 8 8 15 8 0 8 0 15 8 0 0 8 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 8 0 15 8 15 8 0 8 0 8 0 15 0 0 % L
% Met: 0 0 0 8 15 8 0 0 0 0 8 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 15 8 0 15 % N
% Pro: 0 15 8 29 8 0 15 15 15 8 0 8 15 29 43 % P
% Gln: 0 8 15 8 8 0 8 0 0 29 29 8 8 22 0 % Q
% Arg: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 22 8 8 15 0 22 22 43 15 29 15 22 15 15 8 % S
% Thr: 0 8 0 0 8 8 8 22 0 8 0 8 8 0 0 % T
% Val: 8 0 22 0 0 0 0 8 8 0 0 8 8 15 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 22 15 29 0 0 8 8 8 15 8 0 15 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _